Skip to main content

Table 5 Incidence of infectious disease, febrile episodes and dermatitis during the intervention period

From: Evaluation of the safety, tolerance and efficacy of 1-year consumption of infant formula supplemented with Lactobacillus fermentum CECT5716 Lc40 or Bifidobacterium breve CECT7263: a randomized controlled trial

 

Number of events (N)

Incidence Rate

(Standard Error)

Lf vs Control group

Bb vs Control group

 

Control

(61)

Lf group

(65)

Bb group

(63)

Control

Lf group

Bb group

IRR

(95% CI)

p-value

IRR

(95% CI)

p-value

Diarrhoeaa

42

25

49

0.689

(0.106)

0.385

(0.077)

0.778

(0.113)

0.559

(0.326–0.938)

0.014

1.129

(0.745–1.777)

0.750

Upper tract

146

168

132

2.393

(0.212)

2.585

(0.206)

2.096

(0.188)

1.080

(0.829–1.309)

0.673

0.876

(0.663–1.076)

0.223

Lower tract

34

49

44

0.557

(0.101)

0.754

(0.108)

0.700

(0.107)

1.354

(0.814–2.054)

0.190

1.257

(0.756–1.953)

0.293

Conjunctivitis

11

4

8

0.180

(0.054)

0.062

(0.031)

0.127

(0.045)

0.344

(0.080–1.170)

0.071

0.705

(0.246–1.922)

0.473

Otitis

11

11

18

0.180

(0.054)

0.169

(0.051)

0.286

(0.067)

0.939

(0.369–2.387)

0.883

1.589

(0.709–3.712)

0.218

Urine Infection

2

2

1

0.033

(0.023)

0.031

(0.022)

0.016

(0.016)

0.940

(0.069–13.149)

0.958

0.485

(0.008–9.300)

0.540

Fever

32

28

27

0.525

(0.096)

0.431

(0.081)

0.429

(0.084)

0.821

(0.461–1.362)

0.193

0.817

(0.463–1.383)

0.172

Dermatitis

7

2

7

0.115

(0.043)

0.031

(0.022)

0.111

(0.042)

0.270

(0.028–1.430)

0.105

0.965

(0.290–3.235)

0.947

  1. aOf the 42 diarrhea events in the control group, 19 occurred before 6 months and 23 in the period of 6 to 12 months. In the case of the Lf group, of the 25 diarrhea events 8 took place before 6 months and 17 in the period of 6 to 12 months