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Table 3 Comparison with Wilcoxon rank sum test and using Bonferroni step-down correction for p-values

From: Increased liver echogenicity and liver enzymes are associated with extreme obesity, adolescent age and male gender: analysis from the German/Austrian/Swiss obesity registry APV

n (%) Normal liver echogenicity Pathological liver echogenicity P-value Normal liver enzymes (< 25 U/L) Elevated liver Enzymes (> 25 U/L) P-value Normal liver enzymes (< 50 U/L) Elevated liver Enzymes (> 50 U/L) P-value
n = 575
(56%)
n = 458
(44%)
n = 369
(36%)
n = 664
(64%)
n = 859
(83%)
n = 174
(17%)
Mean ± SD Mean ± SD Mean ± SD
Age (years) 12.7 ± 2.9 13.5 ± 2.8 < 0.0001 12.9 ± 2.9 13.1 ± 2.8 n.s. 12.9 ± 2.9 13.8 ± 2.8 0.001
Height (cm) 157.9 ± 14.6 161.6 ± 13.5 n.s. 158.3 ± 14.2 160.2 ± 14.3 n.s. 158.7 ± 14.3 163.9 ± 13.6 n.s.
Weight (kg) 79.4 ± 24.6 90.3 ± 25.5 < 0.0001 79.5 ± 24.4 86.8 ± 25.9 0.003 82.0 ± 24.8 95.3 ± 26.5 < 0.0001
BMI (kg/m2) 31.2 ± 5.9 34.0 ± 6.2 < 0.0001 31.1 ± 6.0 33.2 ± 6.1 < 0.0001 31.9 ± 6.1 34.9 ± 5.9 < 0.0001
AST (U/L) 25.0 ± 15.7 33.3 ± 27.4 < 0.0001 14.4 ± 9.3 35.8 ± 23.1 < 0.0001 23.2 ± 10.4 54.5 ± 38.4 < 0.0001
ALT (U/L) 24.9 ± 23.0 40.1 ± 37.0 < 0.0001 11.9 ± 9.0 42.6 ± 33.3 < 0.0001 22.1 ± 12.3 78.5 ± 47.7 < 0.0001
gammaGT (U/L) 19.7 ± 17.9 27.3 ± 22.9 < 0.0001 14.2 ± 5.2 26.2 ± 23.1 < 0.0001 18.2 ± 7.1 43.7 ± 38.6 < 0.0001
SBP (mmHg) 123.9 ± 14.9 126.3 ± 14.2 n.s. 122.5 ± 15.6 126.3 ± 13.9 0.0002 124.3 ± 14.9 128.1 ± 13.1 0.016
DBP (mmHg) 73.2 ± 10.3 74.3 ± 10.5 n.s. 72.9 ± 10.3 74.1 ± 10.4 n.s. 73.3 ± 10.4 75.8 ± 10.2 0.031
TC (mg/dL) 128.2 ± 72.1 126.0 ± 76.7 n.s. 93.2 ± 81.7 146.5 ± 61.7 < 0.0001 123.8 ± 75.2 144.3 ± 66.1 n.s.
HDL-C (mg/dL) 39.5 ± 35.1 33.0 ± 21.5 < 0.0001 27.7 ± 32.8 41.7 ± 27.0 < 0.0001 36.7 ± 32.1 36.2 ± 16.4 n.s.
LDL-C (mg/dL) 76.5 ± 46.5 76.2 ± 50.9 n.s. 54.9 ± 50.3 88.7 ± 42.8 < 0.0001 73.7 ± 47.9 90.2 ± 49.2 0.016
TG (mg/dL) 78.1 ± 78.0 88.4 ± 73.0 0.014 61.9 ± 77.9 94.5 ± 72.2 < 0.0001 78.6 ± 76.7 102.6 ± 68.8 < 0.0001
Fasting glucose (mg/dL) 69.9 ± 32.6 77.6 ± 50.8 n.s. 52.6 ± 40.0 84.8 ± 38.3 < 0.0001 71.2 ± 44.4 84.4 ± 21.0 0.0002
OGTT (mg/dL) 87.9 ± 43.8 96.5 ± 42.6 n.s. 66.4 ± 52.6 106.6 ± 27.6 < 0.0001 88.2 ± 43.9 110.0 ± 35.9 0.0006
HbA1C (%) 5.3 ± 0.5 5.7 ± 6.1 n.s. 6.1 ± 7.8 5.3 ± 0.4 n.s. 5.6 ± 4.8 5.3 ± 0.6 n.s.
  1. n (number), ALT Alanine-Aminotransferase, AST Aspartat-Aminotransferase, BMI Body Mass Index, DBP Diastolic Blood Pressure, gammaGT gamma Glutamyltransferase, HbA1C Glycated Haemoglobin, HDL-C High Density Lipoprotein Cholesterol, LDL-C Low-Density Lipoprotein Cholesterol, OGTT Oral Glucose Tolerance Test, SBP Systolic Blood Pressure, TC Total Cholesterol, TG Triglycerides, SD Standard Deviation