From: Mortality and severe morbidity of very preterm infants: comparison of two French cohort studies
Neonatal outcomes | Cohort | 24–26 WG, % (n/N) | 27–28 WG, % (n/N) | 29–31 WG, % (n/N) | |
---|---|---|---|---|---|
Death or severe morbiditya | OGP | 74.3 (165/222) | 44.0 (135/307) | 15.5 (115/743) | |
EPIPAGE 2 | 63.2 (500/791)** | 35.3 (297/842)** | 12.5 (254/2036)* | ||
Death | OGP | 45.9 (102/222) | 19.2 (59/307) | 4.7 (35/743) | |
EPIPAGE 2 | 30.3 (240/791)*** | 12.1 (102/842)** | 2.7 (54/2036)** | ||
Severe morbidityb | OGP | 55.3 (63/114) | 32.5 (76/234) | 11.8 (80/677) | |
EPIPAGE 2 | 48.2 (260/539) | 27.7 (195/704) | 10.5 (200/1899) | ||
Bronchopulmonary dysplasia | OGP | 25.7 (56/218) | 19.9 (60/301) | 6.8 (50/732) | |
EPIPAGE 2 | 32.0 (200/625) | 16.8 (127/755) | 4.2 (83/1972)** | ||
Necrotising enterocolitis | OGP | 6.9 (15/218) | 7.3 (22/301) | 3.6 (26/732) | |
EPIPAGE 2 | 4.6 (35/761) | 5.2 (42/812) | 2.6 (53/2006) | ||
Severe neurological injury | OGP | 23.9 (51/213) | 10.8 (31/287) | 3.9 (28/711) | |
EPIPAGE 2 | 26.2 (201/767) | 11.4 (93/817) | 5.4 (107/1993) | ||
Medical patent ductus arteriosus | OGP | 25.2 (55/218) | 15.0 (45/301) | 4.0 (29/733) | |
EPIPAGE 2 | 40.7 (304/747)*** | 33.0 (267/809)*** | 7.9 (155/1969)*** | ||
Surgical patent ductus arteriosus | OGP | 16.5 (36/218) | 8.3 (25/301) | 2.0 (15/732) | |
EPIPAGE 2 | 18.6 (139/747) | 5.3 (43/808) | 0.9 (18/1956)* | ||
Retinopathy | Yes | OGP | 1.8 (4/222) | 1.6 (5/307) | 2.7 (20/743) |
Missing data | 70.7 (157/222) | 73.6 (226/307) | 73.1 (543/743) | ||
Yes | EPIPAGE 2 | 3.7 (29/791)*** | 0.6 (5/842)*** | 0.1 (2/2036)*** | |
Missing data | 20.3 (161/791) | 31.1 (262/842) | 27.5 (560/2036) | ||
Late onset sepsis | OGP | 56.0 (122/218) | 42.2 (127/301) | 14.0 (102/726) | |
EPIPAGE 2 | 65.2 (473/726)* | 49.4 (385/780)* | 24.2 (450/1858)*** |