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Table 2 Distribution of S. pneumoniae isolates with intermediate/full resistance towards four antimicrobials by vaccine coverage. All isolates were sensitive to Levofloxacin

From: Pneumococcal carriage among children under five in Accra, Ghana, five years after the introduction of pneumococcal conjugate vaccine

  Number of isolates tested for susceptibility Number of non-susceptible isolates (% of all isolates) Number of non-typable tested for susceptibility Number of non-susceptible PCV-13 serotypes Number of non-susceptible non-PCV13 serotypes
All isolates 220 191 (86.8%) 10 (4.5%) 76 (34.5%) 144 (65.5%)
PEN (MIC 0.06–2) 220a 49 (22.3%) 7 (3.2%) 27 (12.3) 13 (6.0%)
PEN (MIC > 2) 1 (0.5%) 0 0 1 (0.5%)
TET (25 > I > =22) 219b 2 (0.9%) 0 1 (0.5%) 1 (0.5%)
TET (R < 22) 138 (63.0%) 7 (3.2%) 64 (29.2%) 51 (2.3%)
SXT (18 ≥ I ≥ 15) 220c 32 (14.5%) 1 (0.5%) 10 (4.5%) 18 (8.2%)
SXT (R < 15) 135 (61.4%) 8 (3.6%) 58 (26.4%) 43 (19.5%)
ERY (S ≥ 22 > I ≥ 19) 220d 11 (5.0%) 1 (0.5% 4 (1.8%) 5 ((2.3%)
ERY (R < 19) 24 (10.9%) 0 15 (6.8%) 8 (3.6%)
MDR ≥ 3 220 45 (20.5%) 4 (1.8%) 27 (12.3) 18 (8.2%)
  1. aInformation on Penicillin susceptibility for 14 isolates is not available
  2. bInformation on Tetracycline susceptibility for 15 isolates is not available
  3. cInformation on SXT susceptibility for 14 isolates is not available
  4. dInformation on Erythromycin susceptibility for 14 isolates is not available