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Table 3 Changes in gross motor function and muscle tone after stem cell transplantation according to patient characteristics

From: Improvement in gross motor function and muscle tone in children with cerebral palsy related to neonatal icterus: an open-label, uncontrolled clinical trial

Characteristics Change in GMFM-88 score
Mean [95% CI]
Change in GMFM-66 percentile
Mean [95% CI]
Change in Ashworth score
Mean [95% CI]
Gendera
 Male 32.4 [25.2; 39.5] p-value = 0.808 20.2 [16.7; 23.6] p-value = 0.593 1.0 [0.7; 1.2] p-value = 0.301
 Female 31.1 [26.8;36.9] 18.7 [13.5; 23.9] 0.8 [0.3; 1.2]
Ageb
 < 36 months 37.1 [31.9; 42.3] p-value = 0.368 21.7 [16.2; 27.1] p-value = 0.776 0 p-value = 0.393
 36–72 months 30.9 [22.4; 39.5] 17.9 [13.7; 22.1] 0.8 [0.6; 1.0]
 > 72 months 31.9 [25.1; 38.7] 21.0 [17.1; 25.0] 0.9 [0.5; 1.4]
GMFCSb
 Level II 8.9 [6.0; 11.8] p-value = 0.574 9.6 [1.1; 18.1] p-value = 0.929 0.8 [0.7; 0.9] p-value = 0.316
 Level III 21.1 [12.6; 29.5] 13.9 [6.9; 20.8] 0.6 [0.04; 1.2]
 Level IV 39.5 [31.8; 47.2] 18.6 [15.0; 22.2] 1.0 [0.9; 1.0]
 Level V 34.2 [28.9; 39.4] 22.6 [19.5; 25.7] 0.9 [0.6; 1.3]
  1. at-test
  2. bone-way ANOVA test (Bonferroni test for Post Hoc analysis)