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Table 3 Changes in gross motor function and muscle tone after stem cell transplantation according to patient characteristics

From: Improvement in gross motor function and muscle tone in children with cerebral palsy related to neonatal icterus: an open-label, uncontrolled clinical trial

Characteristics

Change in GMFM-88 score

Mean [95% CI]

Change in GMFM-66 percentile

Mean [95% CI]

Change in Ashworth score

Mean [95% CI]

Gendera

 Male

32.4 [25.2; 39.5]

p-value = 0.808

20.2 [16.7; 23.6]

p-value = 0.593

1.0 [0.7; 1.2]

p-value = 0.301

 Female

31.1 [26.8;36.9]

18.7 [13.5; 23.9]

0.8 [0.3; 1.2]

Ageb

 < 36 months

37.1 [31.9; 42.3]

p-value = 0.368

21.7 [16.2; 27.1]

p-value = 0.776

0

p-value = 0.393

 36–72 months

30.9 [22.4; 39.5]

17.9 [13.7; 22.1]

0.8 [0.6; 1.0]

 > 72 months

31.9 [25.1; 38.7]

21.0 [17.1; 25.0]

0.9 [0.5; 1.4]

GMFCSb

 Level II

8.9 [6.0; 11.8]

p-value = 0.574

9.6 [1.1; 18.1]

p-value = 0.929

0.8 [0.7; 0.9]

p-value = 0.316

 Level III

21.1 [12.6; 29.5]

13.9 [6.9; 20.8]

0.6 [0.04; 1.2]

 Level IV

39.5 [31.8; 47.2]

18.6 [15.0; 22.2]

1.0 [0.9; 1.0]

 Level V

34.2 [28.9; 39.4]

22.6 [19.5; 25.7]

0.9 [0.6; 1.3]

  1. at-test
  2. bone-way ANOVA test (Bonferroni test for Post Hoc analysis)