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Table 2 Gross motor function improvement after stem cell transplantation

From: Improvement in gross motor function and muscle tone in children with cerebral palsy related to neonatal icterus: an open-label, uncontrolled clinical trial

  Baseline
Median (IQR)
6 months post-transplantation
Median (IQR)
p-value at 6 months 12 months post-transplantation
Median (IQR)
p-value at 12 months
Total GMFM-88 score 18.3 (17.6) 35.8 (27.6) 0.0003 53.2 (28.2) 0.0000
Lying and rolling 34.0 (26.0) 48.0 (10.0) 0.0011 51.0 (2.0) 0.0000
Sitting 15.0 (24.0) 38.0 (31.0) 0.0003 56.0 (9.0) 0.0000
Crawling and kneeling 0.0 (5.0) 9.0 (28.0) 0.0001 29.0 (27.0) 0.0000
Standing 0.0 (0.0) 0.0 (4.0) 0.0084 3.0 (14.0) 0.0003
Walking, running and jumping 0.0 (0.0) 0.0 (0.0) 0.0256 0.0 (5.0) 0.0084
GMFM-66 score 26.7 (14.8) 38.4 (12.9) 0.0003 45.6 (10.7) 0.0000
GMFM-66 percentile 19.3 (19.6) 22.5 (22.6) 0.0002 40.1 (5.5) 0.0000
Ashworth score 4.0 (0.25) 3.3 (0.63) 0.0000 3.0 (0.25) 0.0000
  1. IQR Interquartile range
  2. *Significant at p ≤ 0.05