Table 2 Gross motor function improvement after stem cell transplantation
Baseline Median (IQR) | 6 months post-transplantation Median (IQR) | p-value at 6 months | 12 months post-transplantation Median (IQR) | p-value at 12 months | |
|---|---|---|---|---|---|
Total GMFM-88 score | 18.3 (17.6) | 35.8 (27.6) | 0.0003 | 53.2 (28.2) | 0.0000 |
Lying and rolling | 34.0 (26.0) | 48.0 (10.0) | 0.0011 | 51.0 (2.0) | 0.0000 |
Sitting | 15.0 (24.0) | 38.0 (31.0) | 0.0003 | 56.0 (9.0) | 0.0000 |
Crawling and kneeling | 0.0 (5.0) | 9.0 (28.0) | 0.0001 | 29.0 (27.0) | 0.0000 |
Standing | 0.0 (0.0) | 0.0 (4.0) | 0.0084 | 3.0 (14.0) | 0.0003 |
Walking, running and jumping | 0.0 (0.0) | 0.0 (0.0) | 0.0256 | 0.0 (5.0) | 0.0084 |
GMFM-66 score | 26.7 (14.8) | 38.4 (12.9) | 0.0003 | 45.6 (10.7) | 0.0000 |
GMFM-66 percentile | 19.3 (19.6) | 22.5 (22.6) | 0.0002 | 40.1 (5.5) | 0.0000 |
Ashworth score | 4.0 (0.25) | 3.3 (0.63) | 0.0000 | 3.0 (0.25) | 0.0000 |