Skip to main content

Table 3 Distribution and frequency of CMV-gB genotypes along with genotypic Clinical manifestations and viral copy numbers [log10] in congenitally infected symptomatic neonates

From: Genotypes of glycoprotein B gene among the Indian symptomatic neonates with congenital CMV infection

Sample No.

CMV load [log10/ml]

gB genotypes

Clinical significance

1.

3.2 × 103

gB1, gB2

Hepatosplenomegaly, neonatal cholestasis, microcephaly thrombocytopenia, intrauterine growth restriction,

2.

2.7 × 102

gB1

Hepatosplenomegaly, neonatal jaundice, neonatal cholestasis

3.

1.8 × 104

gB2

Thrombocytopenia, intrauterine growth restriction, microcephaly

4.

3.6 × 103

gB1

Hepatosplenomegaly, neonatal jaundice, neonatal cholestasis

5.

5.2 × 103

gB1, gB2

Hepatosplenomegaly, neonatal cholestasis, microcephaly thrombocytopenia, intrauterine growth restriction,

6.

6.8 × 106

gB2

Thrombocytopenia, intrauterine growth restriction, microcephaly

7.

3.8 × 103

gB1, gB3

Hepatosplenomegaly, neonatal jaundice, neonatal cholestasis, bronchopneumonia, septicemia, thrombocytopenia

8.

2.8 × 104

gB5

Septicemia, bronchopneumonia, thrombocytopenia

9.

4.5 × 102

gB3

Bronchopneumonia, septicemia, thrombocytopenia

10.

3.8 × 103

gB5

Septicemia, bronchopneumonia, thrombocytopenia

11.

1.6 × 105

gB3

Bronchopneumonia, septicemia, thrombocytopenia

12.

6.1 × 103

gB1

Hepatosplenomegaly, neonatal jaundice, neonatal cholestasis

13.

5.8 × 103

gB2, gB5

Thrombocytopenia, microcephaly, septicemia, bronchopneumonia, hepatosplenomegaly, intrauterine growth restriction,

14.

3.4 × 103

gB4

Congenital cataract, hearing impairment, microcephaly, hepatosplenomegaly

15.

2.4 × 105

gB2

Thrombocytopenia, intrauterine growth restriction, microcephaly

16.

1.8 × 104

gB3

Bronchopneumonia, septicemia, thrombocytopenia

17.

2.6 × 103

gB1

Hepatosplenomegaly, neonatal jaundice, neonatal cholestasis