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Table 3 Distribution and frequency of CMV-gB genotypes along with genotypic Clinical manifestations and viral copy numbers [log10] in congenitally infected symptomatic neonates

From: Genotypes of glycoprotein B gene among the Indian symptomatic neonates with congenital CMV infection

Sample No. CMV load [log10/ml] gB genotypes Clinical significance
1. 3.2 × 103 gB1, gB2 Hepatosplenomegaly, neonatal cholestasis, microcephaly thrombocytopenia, intrauterine growth restriction,
2. 2.7 × 102 gB1 Hepatosplenomegaly, neonatal jaundice, neonatal cholestasis
3. 1.8 × 104 gB2 Thrombocytopenia, intrauterine growth restriction, microcephaly
4. 3.6 × 103 gB1 Hepatosplenomegaly, neonatal jaundice, neonatal cholestasis
5. 5.2 × 103 gB1, gB2 Hepatosplenomegaly, neonatal cholestasis, microcephaly thrombocytopenia, intrauterine growth restriction,
6. 6.8 × 106 gB2 Thrombocytopenia, intrauterine growth restriction, microcephaly
7. 3.8 × 103 gB1, gB3 Hepatosplenomegaly, neonatal jaundice, neonatal cholestasis, bronchopneumonia, septicemia, thrombocytopenia
8. 2.8 × 104 gB5 Septicemia, bronchopneumonia, thrombocytopenia
9. 4.5 × 102 gB3 Bronchopneumonia, septicemia, thrombocytopenia
10. 3.8 × 103 gB5 Septicemia, bronchopneumonia, thrombocytopenia
11. 1.6 × 105 gB3 Bronchopneumonia, septicemia, thrombocytopenia
12. 6.1 × 103 gB1 Hepatosplenomegaly, neonatal jaundice, neonatal cholestasis
13. 5.8 × 103 gB2, gB5 Thrombocytopenia, microcephaly, septicemia, bronchopneumonia, hepatosplenomegaly, intrauterine growth restriction,
14. 3.4 × 103 gB4 Congenital cataract, hearing impairment, microcephaly, hepatosplenomegaly
15. 2.4 × 105 gB2 Thrombocytopenia, intrauterine growth restriction, microcephaly
16. 1.8 × 104 gB3 Bronchopneumonia, septicemia, thrombocytopenia
17. 2.6 × 103 gB1 Hepatosplenomegaly, neonatal jaundice, neonatal cholestasis