Table 3 Risk factors associated with pulmonary hypertension in children born 1973–2010
From: Increased risk of pulmonary hypertension following premature birth
Variable | Cases N = 128 | Controls N = 768 (missing) | Odds ratio | 95% confidence interval | p-value |
|---|---|---|---|---|---|
Premature birth | 37 | 47 | 4.48 | 2.10–9.52 | 0.0001 |
Female sex | 72 | 346 | 1.69 | 1.06–2.71 | 0.0277 |
Small for gestational age | 7 | 13 | 4.06 | 1.14–14.49 | 0.0310 |
Large for gestational age | 6 | 21 | 3.53 | 1.21–10.31 | 0.0212 |
Chronic pulmonary disease | 15 | 3 | 13.07 | 2.21–77.19 | 0.0046 |
Persistent pulmonary hypertension at birth | 27 | 10 | 15.01 | 5.57–40.44 | 0.0000 |
Congenital heart defect | 23 | 10 | 10.12 | 3.94–25.99 | 0.0000 |
Chromosomal abnormalities | 10 | 1 | 67.71 | 4.70–974.90 | 0.0020 |
Maternal hypertension | 15 | 37 | 2.70 | 1.12–6.54 | 0.0276 |