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Table 2 Odd ratios (95% CIs) for infants with food allergy and eczema in infancy

From: Influence of prenatal and early-life exposures on food allergy and eczema in infancy: a birth cohort study

Variables

Food allergy (n = 200)

Eczema (n = 226)

Univariate

Multivariate†

Univariate

Multivariate†

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

P

No. of older siblings (≥1)

0.68 (0.47, 0.98)

0.042

0.65 (0.44, 0.95)

0.026

    

Solid food introduced < 6 months

1.65 (1.07, 2.55)

0.023

1.76 (1.12, 2.76)

0.014

    

Parental history of allergy

2.41 (1.74, 3.33)

<  0.001

2.45 (1.75, 3.42)

<  0.001

2.00 (1.46, 2.74)

<  0.001

2.14 (1.54, 2.97)

<  0.001

Aquatic products consumption

 < 1 time a week

1.00 (Reference)

 

1.00 (Reference)

     

 1–2 times a week

1.50 (1.01, 2.22)

0.043

1.73 (1.12, 2.67)

0.014

    

 ≥ 3 times a week

1.28 (0.83, 1.96)

0.266

1.49 (0.89, 2.51)

0.132

    

Eggs consumption

 ≤ 2 times a week

1.00 (Reference)

 

1.00 (Reference)

 

1.00 (Reference)

 

1.00 (Reference)

 

 3–4 times a week

0.72 (0.46, 1.13)

0.150

0.61 (0.38, 0.99)

0.047

0.56 (0.36, 0.88)

0.011

0.51 (0.32, 0.81)

0.005

 ≥ 5 times a week

0.88 (0.59, 1.30)

0.510

0.82 (0.51, 1.33)

0.429

0.88 (0.61–1.29)

0.518

0.74 (0.47, 1.17)

0.201

Milk or milk products consumption

 ≤ 2 times a week

    

1.00 (Reference)

 

1.00 (Reference)

 

 3–4 times a week

    

1.65 (1.10–2.48)

0.016

1.81 (1.17, 2.80)

0.008

 ≥ 5 times a week

    

1.44 (0.98–2.11)

0.061

1.35 (0.86, 2.10)

0.194

Exposure to antibiotics during pregnancy

    

3.51 (1.26–9.80)

0.016

3.59 (1.19, 10.85)

0.024

Exposure to antibiotics through medication during the first year

    

0.43 (0.27–0.67)

<  0.001

0.44 (0.28, 0.70)

<  0.001

Season of birth (autumn-winter)

    

1.21 (0.89–1.63)

0.226

1.38 (1.00, 1.91)

0.052

  1. Crude and adjusted ORs(95% CI) and P values were presented for exposure variables significantly associated with food allergy and/or eczema in the multivariate analysis
  2. †Infant’s sex and other exposure variables associated with food allergy and/or eczema during the first year of life with a P value < 0.2 in the univariate analysis were included in the multivariate logistic regression models