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Table 4 Diagnoses and hospitalization outcomes of newborns treated for risk of congenital syphilis

From: Better care for babies: the added value of a modified reverse syphilis testing algorithm for the treatment of congenital syphilis in a maternity Hospital in Central African Republic

  RPRa Reactiveb RPRa Non-reactivec p-value
N=89 (%) N=111 (%)
Discharge Diagnosesd
 None 65 (73) 82 (74) NS
 Sepsis 8 (7) 2 (2) 0.02*
 Perinatal asphyxia 4 (4) 7 (8) NS*
 Premature/low birth weight 3 (3) 3 (3) NS*
 Antibiotic prophylaxis (well baby)e 9 (8) 15 (17) NS
 HIV Exposure 4 (4) 9 (10) NS
Number of diagnoses
 None 65 (73) 82 (74) NS
 One diagnosis 20 (22) 22 (20) NS
 Two diagnoses 4 (5) 7 (6) NS*
Disposition
 Discharged 79 (89) 107 (96) 0.05
 Transferred 2 (2) 0 (0) NS*
 Dead 2 (2) 1 (1) NS*
 Left against medical advice 6 (7) 3 (3) NS*
  1. X2 test used for all comparisons except where indicated as (*) Fisher’s exact test
  2. Neonatal treatment was based on Maternal RPR Results at MSF Castors Maternity Hospital from March 2017 to February 2018
  3. aRPR Rapid plasma reagin test b RPR reactive = titre > 1:4c RPR non-reactive = titre of 1:2
  4. dSum of n for discharge diagnoses is not equal to 100% as patients can present with more than one diagnosis
  5. NS = Not significant
  6. eAntibiotic prophylaxis = infants who are treated for a minimum of 48 h of antibiotics based on maternal and birth risk factors but who are otherwise well