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Table 4 The differences of clinical characteristics, microbiology, CRP and peripheral white cell count indices between children presenting with chronic cough diagnosed with or without laboratory-confirmed pertussis

From: Pertussis detection in children with cough of any duration

 

Laboratory confirmed pertussisa

P value

Yes

N = 26

No

N = 87

Age group (months)

 0 - <12, n(%)

14 (53.9)

27 (31.0)

0.0686

 12–36, n(%)

2 (7.7)

19 (21.8)

 

 36 +, n(%)

10 (38.5)

41 (47.1)

 

Gender

 Male, n(%)

17 (65.4)

60 (69.0)

0.7310

 Female, n(%)

9 (34.6)

27 (31.0)

 

Contact with cough patient

 Yes, n(%)

14 (53.9)

39 (44.8)

0.4188

 No, n(%)

12 (46.2)

48 (55.2)

 

Clinical features

 Fever, n(%)

11 (42.3)

39 (44.8)

0.8204

 Apnea, n(%)

2 (7.7)

2(2.3)

0.1916

 Cyanosis, n(%)

3 (11.5)

3(3.5)

0.1065

Cough characteristic

 Whoop, n(%)

8 (30.8)

20 (23.0)

0.4200

 Paroxysm, n(%)

17 (65.4)

38 (43.7)

0.0520

 Wet/Productive, n(%)

12 (46.2)

31 (35.6)

0.3323

 Nocturnal cough, n(%)

6 (23.1)

22 (25.3)

0.8188

 Post-tussive vomiting, n(%)

9 (34.6)

28 (32.2)

0.8167

Other pathogen positive

 Immunofluorescence (N = 79)

N = 17

N = 62

 

 Any virus positive, n(%)

6 (35.3)

9 (14.5)

0.0530

 IgM for MP, CP,RSV and LP (N = 106)

N = 25

N = 81

 

 MP - IgM positive, n(%)

1 (4.0)

7 (8.6)

0.4424

 CP –IgM positive, n(%)

0(0)

2(2.5)

0.4277

 RSV – IgM positive, n(%)

1 (4.0)

7 (8.6)

0.4424

 LP – IgM positive, n(%)

0(0)

8 (9.9)

0.1022

 Peripheral white cell count indices and CRP (N = 107)

N = 25

N = 82

 

 Peripheral wbc count(median, IQR)

9.0 (6.3–15.6)

9.1 (7.2–12.3)

0.7600

 Neutrophil absolute count(median, IQR)

3.1 (1.8–4.5)

3.5 (2.2–4.9)

0.2344

 Lymphocyte absolute count(median, IQR)

4.3 (2.7–8.9)

3.9 (2.6–6.4)

0.6454

 CRP(median, IQR)

1.8 (0.3–4.6)

1.4 (0.1–6.6)

0.7982

  1. aEither definite pertussis or probable pertussis was considered as laboratory confirmed pertussis in this study