Table 3 The differences of clinical characteristics, microbiology, CRP and peripheral white cell count indices between children presenting with sub-acute cough diagnosed with or without laboratory-confirmed pertussis
From: Pertussis detection in children with cough of any duration
Laboratory confirmed pertussisa | P value | ||
|---|---|---|---|
Yes N = 37 | No N = 43 | ||
Age group (months) | |||
0 - <12, n(%) | 29(78.4) | 31(72.1) | 0.1936 |
12–36, n(%) | 7(18.9) | 6(14.0) | |
36 +, n(%) | 1(2.7) | 6(14.0) | |
Gender | |||
Male, n(%) | 25(67.6) | 30(69.8) | 0.8324 |
Female, n(%) | 12(32.4) | 13(30.2) | |
Contact with cough patient | |||
Yes, n(%) | 20(54.1) | 29(67.4) | 0.2204 |
No, n(%) | 17(46.0) | 14(32.6) | |
Clinical features | |||
Fever, n(%) | 5 (13.5) | 17(39.5) | 0.0094 |
Apnea, n(%) | 7(18.9) | 6(14.0) | 0.5483 |
Cyanosis, n(%) | 8(21.6) | 7(16.3) | 0.5416 |
Cough characteristic | |||
Whoop, n(%) | 20(54.1) | 9(20.9) | 0.0021 |
Paroxysm, n(%) | 32 (86.5) | 32 (74.4) | 0.1785 |
Wet/Productive, n(%) | 20(54.1) | 18 (41.9) | 0.2762 |
Nocturnal cough, n(%) | 25(67.6) | 21 (48.8) | 0.0911 |
Post-tussive vomiting, n(%) | 18 (48.7) | 24 (55.8) | 0.5223 |
Other pathogen positive | |||
Immunofluorescence (N = 73) | N = 34 | N = 39 | |
Any virus positive, n(%) | 12 (35.3) | 10 (25.6) | 0.3699 |
IgM for MP, CP,RSV and LP (N = 73) | N = 33 | N = 40 | |
MP - IgM positive, n(%) | 0(0) | 0(0) | – |
CP –IgM positive, n(%) | 0(0) | 2 (5.0) | 0.1927 |
RSV – IgM positive, n(%) | 1 (3.0) | 1(2.5) | 0.8901 |
LP – IgM positive, n(%) | 0(0) | 4 (10.0) | 0.0617 |
Peripheral white cell count indices and CRP (N = 76) | N = 32 | N = 42 | |
Peripheral wbc count(median, IQR) | 11.2 (8.4–16.5) | 10.5(8.2–14.0) | 0.4918 |
Neutrophil absolute count(median, IQR) | 2.6 (1.8–3.5) | 2.2(1.4–3.8) | 0.4884 |
Lymphocyte absolute count(median, IQR) | 7.6 (4.7–10.9) | 7.3(3.7–9.5) | 0.3342 |
CRP(median, IQR) | 0.1 (0.1–3.8) | 0.1 (0.1–4.5) | 0.8594 |