Table 2 The differences of clinical characteristics, microbiology, CRP and peripheral white cell count indices between children presenting with acute cough diagnosed with or without laboratory-confirmed pertussis
From: Pertussis detection in children with cough of any duration
Laboratory confirmed Pertussisa | P value | ||
|---|---|---|---|
Yes N = 34 | No N = 85 | ||
Age group (months) | |||
0 - <12, n(%) | 22(64.7) | 61(71.8) | 0.3491 |
12–36, n(%) | 5(14.7) | 15(17.7) | |
36 +, n(%) | 7(20.6) | 9(10.6) | |
Gender | |||
Male, n(%) | 16(47.1) | 62(72.9) | 0.0073 |
Female, n(%) | 18(52.9) | 23(27.1) | |
Contact with cough patient | |||
Yes, n(%) | 20(58.8) | 40(47.1) | 0.2462 |
No, n(%) | 14(41.2) | 45(52.9) | |
Clinical features | |||
Fever, n(%) | 11(32.4) | 32(37.7) | 0.5871 |
Apnea, n(%) | 6(17.7) | 5(5.9) | 0.0453 |
Cyanosis, n(%) | 10(29.4) | 9(10.6) | 0.0113 |
Cough characteristic | |||
Whoop, n(%) | 7(20.6) | 10(11.8) | 0.2140 |
Paroxysm, n(%) | 28(82.4) | 64(75.3) | 0.4062 |
Wet/Productive, n(%) | 16(47.1) | 42(49.4) | 0.8166 |
Nocturnal cough, n(%) | 15(44.1) | 31(36.5) | 0.4390 |
Post-tussive vomiting, n(%) | 9(26.5) | 26(30.6) | 0.6561 |
Other pathogens positive | N = 30 | N = 72 | |
Immunofluorescence (N = 102) | |||
Any virus positive, n(%) | 12(40.0) | 33(45.8) | 0.5888 |
IgM for MP, CP,RSV and LP (N = 110) | N = 32 | N = 78 | |
MP - IgM positive, n(%) | 0(0) | 3(3.9) | 0.2607 |
CP –IgM positive, n(%) | 4(12.5) | 3(3.9) | 0.0913 |
RSV – IgM positive, n(%) | 2(6.3) | 2(2.6) | 0.3483 |
LP – IgM positive, n(%) | 4(12.5) | 7(9.0) | 0.5756 |
Peripheral white cell count indices and CRP (N = 115) | N = 34 | N = 81 | |
Peripheral wbc count(median, IQR) | 12.2(9.4–17.2) | 10.5(8.0–14.9) | 0.2673 |
Neutrophil absolute count(median, IQR) | 3.1(2.3–5.4) | 3.2(1.8–6.1) | 0.9536 |
Lymphocyte absolute count(median, IQR) | 7.4(3.3–12.8) | 5.2(2.8–7.9) | 0.0509 |
CRP(median, IQR) | 1.6(0.1–6.1) | 2.7(0.1–7.7) | 0.4815 |