Table 5 Review of reported cases with juvenile Behçet’s disease who received anti-tumor necrosis factor alpha therapy in the literature
From: Clinical manifestations and anti-TNF alpha therapy of juvenile Behçet’s disease in Taiwan
Case | Sex | Age at diagnosis | Age at aTNF | aTNF | Major organ involvement | Efficacy | Side effect | Reference |
|---|---|---|---|---|---|---|---|---|
1 | Female | 13 | 15 | IFX | Intestinal lesion | (+) | None | Saulsbury et al. (2003), USA [14] |
2 | Male | nr | 12 | IFX | Budd-Chiari syndrome | (−) | None | Seyahi et al. (2007), Turkey [38] |
3 | Male | 15 | 15 | IFX | Budd-Chiari syndrome | (−) | None | |
4 | Female | 13 | 15 | IFX | Ocular lesion | (+) | None | Evereklioglu et al. (2007), Turkey [37] |
5 | Female | 10 | 11 | ETN | Ocular lesion | (+) | Fever | Cantarini et al. (2009), Italy [36] |
6 | Female | 9 | 13 | ETN | Cutaneous lesion | (+) | Bacterial endocarditis | |
7 | Male | 12 | 14 | ETN | Cutaneous lesion | (+) | None | |
8 | Female | 11 | 13 | ETN | Cutaneous lesion | (+) | Fatigue | |
9 | Male | 8 | 18 | IFX | Intestinal lesion | (+) | None | Kaneko et al. (2010), Japan [15] |
10 | Female | 4 | 9 | ETN | Cutaneous lesion | (+) | None | |
11 | Female | 10 | 12 | ADA | Central nervous system | (+) | None | Robinson et al. (2010), USA [35] |
12 | Female | 5 | 5 | IFX | Intestinal lesion | nra | Infusion reaction | Watanabe et al. (2013), Japan [16] |
ETN | (+) | None |