|
Associated factors
|
PaO2
|
PaCO2
|
pH
|
|---|
|
Age
|
−0.06 (− 0.05–0.01)
|
0.00 (− 0.01–0.02)
|
0.00 (0.00–0.00)
|
|
CCC
|
10.05 (−3.70–23.80)
|
−1.97 (− 8.76–4.83)
|
−0.02 (− 0.06–0.02)
|
|
Prematurity
|
14.21 (2.42–26.02)*
|
0.72 (− 4.32–5.77)
|
−0.003 (− 0.05–0.04)
|
|
HFOV
|
− 16.48 (− 28.77 - -4.18)*
|
9.44 (2.29–16.59)*
|
−0.08 (− 0.13 - -0.02)*
|
|
iNO
|
−12.16 (− 24.60–0.27)
|
6.78 (− 0.18–13.75)
|
− 0.01 (− 0.07–0.05)
|
|
P-S
|
10.29 (−2.89–23.48)
|
−4.64 (− 12.87–3.59)
|
0.02 (− 0.06–0.10)
|
|
Time interval adm - surf
|
−0.02 (− 0.26–0.21)
|
0.19 (− 0.04–0.42)
|
−0.001 (− 0.00–0.00)
|
|
Outcome
|
−19.55 (− 34.28 - -4.84)*
|
5.60 (− 2.63–13.85)
|
−0.003 (− 0.09–0.09)
|
- CCC Chronic Complex Condition, HFOV high frequency oscillatory ventilation, iNO inhaled nitric oxide, P-S prono supination, adm admission, surf surfactant dose; * = p < 0.05.
- Multivariate models of analysis of variance for repeated measures were fitted to find associations between demographic or clinical factors and each blood gas or pH variations. Results are presented with term specific p-values; the coefficient represents the mean variation of outcomes for unit change of quantitative predictors or between levels of categorical or ordinal predictors.
