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Table 1 Patient characteristics according to initial choice of neuroimaging

From: Head ultrasound, CT or MRI? The choice of neuroimaging in the assessment of infants with congenital cytomegalovirus infection

 

Overall

Head US first (or sole imaging modality) (n = 39)

CT or MRI first (or sole imaging modality (n = 7)

p

Birthweight (g)

(mean + SD)

2707 ± 741

2738 ± 791

2540 ± 405

0.54

Gestational age (weeks) (mean, SD)

38.0 ± 2.79

38.0 ± 0.98

38.2 ± 3.02

0.85

Presence of clinically apparent symptomsa

24 (54%)

20 (57.1%)

4 (51.2%)

0.78

Microcephaly

5 (11%)

4 (12%)

1 (14%)

0.89

Laboratory abnormalitiesb

22 (48%)

18 (46.1%)

4 (57.1%)

0.59

Sensineural hearing lossc

19 (41.3%)

13 (33%)

6 (85.7%)

< 0.01

CMV tested on clinical suspicion vs. screening program

28 (61%_)

24 (57.1%)

4 (61.5%)

0.83

  1. a Clinically apparent symptoms: Microcephaly, IUGR, hepatomegaly, splenomegaly, petechiea or purpura, jaundice
  2. b Laboratory abnormalities: Any of persistent thrombocytopenia, hepatitis, hyperbilirubinemia
  3. c Defined as a unilateral or bilateral hearing threshold of > 40 dB for at least 2 of the frequencies tested, using a combined protocol of automated distorsion product otoacoustic emissions (DPOAE-A) and automated auditory brainstem response (A-ABR), followed by brainstem auditory evoked potentials by three weeks of age