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Table 1 Patient characteristics according to initial choice of neuroimaging

From: Head ultrasound, CT or MRI? The choice of neuroimaging in the assessment of infants with congenital cytomegalovirus infection

  Overall Head US first (or sole imaging modality) (n = 39) CT or MRI first (or sole imaging modality (n = 7) p
Birthweight (g)
(mean + SD)
2707 ± 741 2738 ± 791 2540 ± 405 0.54
Gestational age (weeks) (mean, SD) 38.0 ± 2.79 38.0 ± 0.98 38.2 ± 3.02 0.85
Presence of clinically apparent symptomsa 24 (54%) 20 (57.1%) 4 (51.2%) 0.78
Microcephaly 5 (11%) 4 (12%) 1 (14%) 0.89
Laboratory abnormalitiesb 22 (48%) 18 (46.1%) 4 (57.1%) 0.59
Sensineural hearing lossc 19 (41.3%) 13 (33%) 6 (85.7%) < 0.01
CMV tested on clinical suspicion vs. screening program 28 (61%_) 24 (57.1%) 4 (61.5%) 0.83
  1. a Clinically apparent symptoms: Microcephaly, IUGR, hepatomegaly, splenomegaly, petechiea or purpura, jaundice
  2. b Laboratory abnormalities: Any of persistent thrombocytopenia, hepatitis, hyperbilirubinemia
  3. c Defined as a unilateral or bilateral hearing threshold of > 40 dB for at least 2 of the frequencies tested, using a combined protocol of automated distorsion product otoacoustic emissions (DPOAE-A) and automated auditory brainstem response (A-ABR), followed by brainstem auditory evoked potentials by three weeks of age