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Table 1 Comparison of clinical characteristics and vaccination status between rotavirus-related acute gastroenteritis cases with and without rotavirus antigen in serum samples

From: Rotavirus antigenemia as a common event among children hospitalised for severe, acute gastroenteritis in Belém, northern Brazil

Characteristics [N*] Children with rotavirus-positive stools (N = 109) P value**
Rotavirus-positive in paired sera Rotavirus-negative in paired sera
N (%) 95% CI N (%) 95% CI
Ruuska & Vesikari score†‡ [105]
 ≥11 (severe) 13 (30.9) 19.1-46.0 29 (46.0) 34.3-58.2 0.1557
 ≥15 (very severe) 29 (69.1) 53.9-80.9 34 (54.0) 41.8-65.7
Axillary temperature (°C)£ [107]
 <37.5 11 (26.2) 15.3-41.1 18 (27.7) 18.3-39.6 1.0000
 ≥37.5 31 (73.8) 15.3-41.1 47 (72.3) 60.4-81.7
Episodes of vomiting/24h [109]
 ≤3 7 (16.7) 8.3-30.6 30 (44.8) 33.5-56.6 0.0035
 >3 35 (83.3) 69.4-91.7 37 (55.2) 44.4-66.5
Duration of vomiting (days) [109]
 ≤3 34 (80.9) 66.7-90.0 55 (82.1) 71.3-89.5 1.0000
 >3 08 (19.1) 9.9-33.3 12 (17.9) 10.6-28.8
Episodes of diarrhoea/24h§ [108]
 ≤3 5 (11.9) 5.2-25.0 13 (19.7) 11.9-30.8 0.4277
 >3 37 (88.1) 75.0-94.8 53 (80.3) 69.2-88.1
Duration of diarrhoea (days) [109]
 ≤3 31 (73.8) 58.9-84.7 47 (70.0) 58.3-79.8 0.8278
 >3 11 (26.2) 15.3-41.1 20 (30.0) 20.2-41.7
Leucocytes/ mm3|| [108]
 ≤10.000 31 (73.8) 58.9-84.7 56 (84.8) 74.3-91.6 0.2126
 >10.000 11 (26.2) 15.3-41.1 10 (15.2) 8.4-25.7
Rotavirus vaccination [85]
 Unvaccinated 8 (25.8) 13.7-43.3 3 (5.6) 1.9-15.1 0.0151
 At least one dose 23 (74.2) 56.8-86.3 51 (94.4) 84.9-98.1
  1. *Number of patients with available data for evaluation
  2. **Fisher test
  3. 20 points Ruuska & Vesikari score (1990)
  4. Not available for 2 patients; moderate score for 2 patients, not included
  5. £ Not available for 2 patients
  6. § Not available for 1 patient
  7. || Not available for 1 patient
  8. Vaccination status not available for 24 patients