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Table 3 The treatment protocols of NEC infants treated (with/without) probiotics in this study

From: Probiotics may not prevent the deterioration of necrotizing enterocolitis from stage I to II/III

Variables

Total (n = 231)

Before matching

After matchinga

With (n = 108)

Without (n = 123)

P

With (n = 81)

Without (n = 81)

P

Gastrointestinal decompression, %(n)

64.1 (148)

57.4 (62)

69.9 (86)

0.048

58.0 (47)

67.9 (55)

0.193

Duration of gastrointestinal decompression, IQR, d

4 (2–6)

3 (2–6)

4 (2–6)

0.319

3 (2–6)

6 (2–6)

0.643

Red blood cell transfusion, %(n)

23.4 (54)

26.9 (29)

20.3 (25)

0.242

22.2 (18)

23.5 (19)

0.852

Platelet support, %(n)

6.5 (15)

7.4 (8)

5.7 (7)

0.597

8.6 (7)

7.4 (6)

0.772

Plasma support, %(n)

13.0 (30)

12.0 (13)

13.8 (17)

0.687

12.3 (10)

13.6 (11)

0.815

Intravenous immunoglobulin, %(n)

13.4 (31)

16.7 (18)

10.6 (13)

0.175

14.8 (12)

12.3 (10)

0.646

Albumin support, %(n)

43.7 (101)

41.7 (45)

45.5 (56)

0.555

38.3 (31)

44.4 (36)

0.425

Dopamine support, %(n)

25.5 (59)

25.0 (27)

26.0 (32)

0.860

23.5 (19)

24.7 (20)

0.854

Caffeine support, %(n)

9.1 (21)

9.3 (10)

8.9 (11)

0.934

8.6 (7)

7.4 (6)

0.772

  1. aWe performed 1:1 matching according to close gestational age (difference was ≤3 days) and birth weight (difference was ≤400 g)