Table 1 The baseline information of NEC infants treated (with/without) probiotics in this study
From: Probiotics may not prevent the deterioration of necrotizing enterocolitis from stage I to II/III
Variables | Total (n = 231) | Before matching | After matchinga | ||||
|---|---|---|---|---|---|---|---|
With (n = 108) | Without (n = 123) | P | With (n = 81) | Without (n = 81) | P | ||
Gestational age, IQR, wks | 37.86 (34.57–39.71) | 37.07 (34.04–39.25) | 38.43 (35.14–39.86) | 0.025 | 37.29 (34.71–38.86) | 38.14 (34.86–39.50) | 0.128 |
Premature, %(n) | 39.4 (91) | 46.3 (50) | 33.3 (41) | 0.044 | 42.0 (34) | 35.8 (29) | 0.420 |
Birth weight, (±SD), g | 2800 (2000–3305) | 2620 (1927.5–3180) | 3000 (2100–3400) | 0.015 | 2591.81 ± 718.45 | 2705.19 ± 713.69 | 0.315 |
Male, %(n) | 40.7 (94) | 48.9 (46) | 51.1 (48) | 0.582 | 47.1 (32) | 52.9 (36) | 0.524 |
Vaginal delivery, %(n) | 42.0 (97) | 38.0 (41) | 45.5 (56) | 0.245 | 39.5 (32) | 46.9 (38) | 0.341 |
The age of onset, IQR, d | 3.44 (1.1–11.1) | 5.49 (1.33–11) | 3.14 (1–13) | 0.355 | 5.57 (1.1–10.1) | 3.4 (1–13.5) | 0.988 |
PROM> 18 h, %(n) | 5.2 (12) | 2.8 (3) | 7.3 (9) | 0.121 | 2.5 (2) | 6.2 (5) | 0.440 |
Amniotic fluid contamination, %(n) | 13.4 (31) | 13.9 (15) | 13.0 (16) | 0.845 | 16.0 (13) | 12.3 (10) | 0.499 |
Asphyxia, %(n) | 10.8 (25) | 9.3 (10) | 12.2 (15) | 0.474 | 11.1 (9) | 13.6 (11) | 0.633 |
Infants of diabetic mothers, %(n) | 2.6 (6) | 3.7 (4) | 1.6 (2) | 0.565 | 3.7 (3) | 2.5 (2) | 1.000 |
PIH, %(n) | 5.6 (13) | 8.3 (9) | 3.3 (4) | 0.095 | 8.6 (7) | 4.9 (4) | 0.349 |
ICP, %(n) | 2.2 (5) | 2.8 (3) | 1.6 (2) | 0.883 | 2.5 (2) | 1.2 (1) | 1.000 |
Antenatal corticosteroids, %(n) | 3.5 (8) | 6.5 (7) | 0.8 (1) | 0.047 | 6.2 (5) | 1.2 (1) | 0.212 |