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Table 1 Summary of the literature review

From: Growth data and tumour risk of 32 Chinese children and adolescents with 45,X/46,XY mosaicism

Year Nation Author Cases NO.
< 18 Y
Other congenital
abnormalities
Height
<− 2.0 SDS
Gonadal histology
1990 USA Chang3 76 / 5 / OT2/3;PTL 1/3
1999 France Telvi16 27 27 8 23 CGD9/27,PGD7/27,MGD11/27
2005 Greece Patsalis23 11 / 4 / CGD8/11,PGD1/11,MGD2/11
2009 USA Kibar24 14 14 2 / CGD2/9, MGD7/9
2010 USA Tosson17 16 16 / 8 CGD3/15,PGD4/15, MGD9/15;GB2/15
2012 France Martinerie18 20 20 9 14 PGD1/18,MGD17/18
2012 Denmark Lindhardt22 25 15 3 / CGD3/15,PGD5/15,MGD6/15,OT1/15
2012 Turkey Ocal10 11 11 / / CGD2/11,PGD4/11,MGD4/11,OT1/11
2013 UK Farrugia25 31 31 15 / /
2014 Brazil Rosa15 14 12 4 6 /
2015 China Chen19 7 7 / 7 /
2015 USA Dendrinos28 16 16 / / GB4/16
2016 China Jiang26 32 / 3 / CGD26/31,PGD5/31;GB4/Seminoma1(5/32)
2016 China Tam29 21 21 / / CGD9/20,PGD11/20; CIS + GB 9/20
2017 China Wu20 16 5 1 9 CGD2/2
2018 Iran Mohammadpour30 49 / / / PGD11/11
2018 China Huang21 19 19 5 15 CGD11/18,PGD2/18,MGD5/18;GB2/18
  405 214 59 (59/285) 82 CGD75/191,PGD51/191, MGD61/191,OT4/191;
  (82/119) GB + CIS + PLT + Seminoma21/104
2018 China Our study 32 32 5 (5/32) 17 (17/27) CGD12/25,PGD3/25,MGD9/25,OT1/25; GB3/25
  1. Y years; CGD complete gonadal dysgenesis; PGD partial gonadal dysgenesis; MGD mixed gonadal dysgenesis; OT ovotesticular tissue; / not specified;
  2. PTL precancerous testicular lesion; GB gonadoblastoma; CIS carcinoma-in situ