Table 2 Difference between acute anti-seizure medication in the group treated with valproic acid and the group treated with levetiracetam matched by gender and main convulsion type variables
Valproic acid | Levetiracetam | ||||||
|---|---|---|---|---|---|---|---|
N | n | % | N | n | % | p-value | |
Etiology | 17 | 17 | |||||
Ischemic infarction | 3 | 17.65 | 7 | 41.18 | |||
HIE 2 | 2 | 11.76 | 0 | 0.00 | |||
HIE 3 | 0 | 0.00 | 1 | 5.88 | |||
Intracranial hemorrhage | 4 | 23.53 | 2 | 11.76 | |||
Intracranial infection | 3 | 17.65 | 0 | 0.00 | |||
Cerebral malformation | 0 | 0.00 | 1 | 5.88 | |||
Metabolic disorder | 1 | 5.88 | 0 | 0.00 | |||
Inborn error of metabolism | 0 | 0.00 | 1 | 5.88 | |||
Benign epileptic syndromes | 3 | 17.65 | 3 | 17.65 | |||
Severe epileptic syndromes | 1 | 5.88 | 1 | 5.88 | |||
Unknown | 0 | 0.00 | 1 | 5.88 | |||
Number of emergency drugs | 17 | 16 | 0.012 | ||||
0 | 1 | 5.88 | 1 | 6.25 | |||
1 | 1 | 5.88 | 8 | 50.00 | |||
2 | 7 | 41.18 | 6 | 37.50 | |||
3 | 8 | 47.06 | 1 | 6.25 | |||
First-line emergency drug | 17 | 16 | 0.097 | ||||
0 | 1 | 5.88 | 1 | 6.25 | |||
diazepam | 9 | 52.94 | 3 | 18.75 | |||
phenobarbital | 5 | 29.41 | 12 | 75.00 | |||
phenytoin | 1 | 5.88 | |||||
clonazepam | 1 | 5.88 | |||||
Second-line emergency drug | 15 | 7 | 0.700 | ||||
diazepam | 1 | 6.67 | |||||
phenobarbital | 9 | 60.00 | 3 | 42.86 | |||
phenytoin | 4 | 26.67 | 3 | 42.86 | |||
clonazepam | 1 | 6.67 | 1 | 14.29 | |||
Third-line emergency drug | 8 | 1 | 0.708 | ||||
phenytoin | 7 | 87.50 | 1 | 100.00 | |||
clonazepam | 1 | 12,50 | |||||