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Table 3 Main causes of drug related problems (DRP) according to the PCNE classification version 6.2

From: Drug related problems in the neonatal intensive care unit: incidence, characterization and clinical relevance

Causes of DRP (n = 1142)

n

%

C3- Dose selection

454

39.7

 C3.1- Drug dose too low

154

13.5

 C3.3- Dosage regimen not frequent enough

124

10.9

 C3.2- Drug dose too high

117

10.2

 C3.7- Deterioration or improvement of disease state requiring dose adjustment

38

3.3

 C3.4- Dosage regimen too frequent

21

1.8

C5- Drug use process

373

32.7

 C5.5- Wrong drug administered

164

14.4

 C5.1- Inappropriate timing of administration and/or dosing intervals

103

9.0

 C5.4- Drug not administered at all

70

6.1

 C5.2- Drug under-administered

36

3.2

C6- Logistics

187

16.4

 C6.2- Prescription error (necessary information missing)

157

13.8

 C6.1- Prescribed drug not available

30

2.6

C1- Drug selection

52

4.5

 C1.3- Inappropriate combination of drugs, or drugs and food

35

3.1

 C1.8- Synergistic or preventive drug required and not given

6

0.5

 C1.4- Inappropriate duplication of therapeutic group or active ingredient

4

0.3

 C1.5- Indication for drug treatment not noticed

4

0.3

 C1.2- No indication for drug

2

0.2

 C1.1- Inappropriate drug

1

0.1

C8- Other

76

6.7

 C8.1- Others specific causes

76

6.7

 C8.2- No obvious cause

0

0