| Optimum diagnostic cut-off level | AUC (95% CI) | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) |
---|---|---|---|---|---|---|
Cerebrospinal fluid markers | ||||||
 CD64in | 1.29 | 0.875 (0.713–0.963) | 92 | 75 | 71 | 94 |
 Leukocyte count (×106/L) | 187 | 0.694 (0.507–0.844) | 69 | 68 | 60 | 77 |
 Percentage of N (%) | 35 | 0.615 (0.428–0.781) | 92 | 47 | 55 | 90 |
 Glucose (mmol/L) | 2.1 | 0.666 (0.478–0.822) | 77 | 53 | 53 | 77 |
 Proteins (g/L) | 0.41 | 0.658 (0.470–0.815) | 100 | 32 | 50 | 100 |
Blood markers | ||||||
 Leukocyte count (×109/L) | 14.4 | 0.504 (0.325–0.682) | 39 | 95 | 83 | 70 |
 Percentage of N (%) | 55 | 0.694 (0.496–0.850) | 50 | 82 | 67 | 70 |
 Percentage of BN (%) | 2 | 0.721 (0.524–0.870) | 50 | 100 | 100 | 74 |
 CRP (mg/L) | 5 | 0.792 (0.616–0.913) | 85 | 75 | 69 | 88 |
 PCT (μg/L) | 0.17 | 0.716 (0.507–0.873) | 85 | 54 | 65 | 78 |