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Table 4 Predictive values for PNAC of laboratory evaluation at 2 weeks after PN

From: Predictive value of the aspartate aminotransferase to platelet ratio index for parenteral nutrition associated cholestasis in extremely low birth weight infants

  Cut-point value PNAC Sensitivity% Specificity% PPV % NPV %
Yes No
DB > 0.7 32 27 57.1% 75.2% 54.2% 77.4%
≤0.7 24 82
APRI > 0.41 43 42 76.8% 62.2% 50.6% 84.1%
≤0.41 13 69
DB, APRI > 0.7 and > 0.41 28 9 50.0% 91.7% 75.7% 78.1%
≤0.7 or ≤ 0.41 28 100
  1. Abbreviations: DB direct bilirubin, PNAC parenteral nutrition–associated cholestasis, APRI aspartate aminotransferase/platelet ratio index
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