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Table 4 Predictive values for PNAC of laboratory evaluation at 2 weeks after PN

From: Predictive value of the aspartate aminotransferase to platelet ratio index for parenteral nutrition associated cholestasis in extremely low birth weight infants

 

Cut-point value

PNAC

Sensitivity%

Specificity%

PPV %

NPV %

Yes

No

DB

> 0.7

32

27

57.1%

75.2%

54.2%

77.4%

≤0.7

24

82

APRI

> 0.41

43

42

76.8%

62.2%

50.6%

84.1%

≤0.41

13

69

DB, APRI

> 0.7 and > 0.41

28

9

50.0%

91.7%

75.7%

78.1%

≤0.7 or ≤ 0.41

28

100

  1. Abbreviations: DB direct bilirubin, PNAC parenteral nutrition–associated cholestasis, APRI aspartate aminotransferase/platelet ratio index