Skip to main content

Table 1 Analysis of risk factors affecting PNAC

From: Predictive value of the aspartate aminotransferase to platelet ratio index for parenteral nutrition associated cholestasis in extremely low birth weight infants

Variable

PNAC

Yes

No

P -value

Gestational age (weeks)

 Mean ± SD

26.07 ± 2.23

26.78 ± 2.32

.035 2

Birth weight (gram)

 Mean ± SD

737.68 ± 151.71

824.72 ± 160.26

.001 2

Hospital days

116.86 ± 56.96

94.34 ± 37.46

.003 2

IUGR

 Yes

20 (35.7)

30 (24.4)

.117 1

 No

36 (64.3)

93 (75.6)

 

Sex

 Male

27 (48.2)

55 (44.7)

.663 1

 Female

29 (51.8)

68 (55.3)

 

Apgar score 1 min

4.38 ± 1.61

4.82 ± 1.31

.085 2

Apgar score 5mins

6.70 ± 1.29

6.93 ± 0.98

.230 2

Ventilator duration (days)

55.79 ± 47.23

29.26 ± 25.69

.000 2

PDA

 Surgical ligation

19 (33.9)

22 (17.9)

.018 1

 Others

37 (66.1)

101 (82.1)

 

ROP

 Laser or bevacizumab inj.

38 (67.9)

59 (48.0)

.013 1

 Observation

18 (32.1)

64 (52.0)

 

Head ultrasonography

 Normal

35 (62.5)

87 (70.7)

.273 1

 Abnormal

21 (37.5)

36 (29.3)

 

BPD

 Yes

45 (80.4)

67 (54.5)

.001 1

 No

11 (19.6)

56 (45.5)

 

NEC

 Yes

27 (48.2)

15 (12.2)

.000 1

 No

29 (51.8)

108 (87.8)

 

Sepsis

 Yes

40 (71.4)

61 (49.6)

.006 1

 No

16 (28.6)

62 (50.4)

 

GI surgery

 Yes

19 (33.9)

9 (7.3)

.000 1

 No

37 (66.1)

114 (92.7)

 

TPN days

 Mean ± SD

74.13 ± 50.62

42.38 ± 31.74

.000 2

Feeding start (days)

 Mean ± SD

4.36 ± 3.25

3.86 ± 2.60

.234 2

Days to achieve full enteral feeding (days)

56.24 ± 22.36

35.06 ± 15.95

.000 2

Type of formula

 Breast milk

20 (37.7)

73 (59.8)

.007 1

 Others

33 (62.3)

49 (40.2)

 
  1. Abbreviations: IUGR intrauterine grow retardation, PDA patent ductus arteriosus, ROP retinopathy of prematurity, BPD bronchopulmonary dysplasia, NEC necrotizing enterocolitis, TPN total parenteral nutrition, PNAC parenteral nutrition–associated cholestasis
  2. 1P values were derived from chi-square test
  3. 2P values were derived from Mann-Whitney’s U test. Shapiro-Wilk’s test was employed for test of normality assumption