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Fig. 2 | BMC Pediatrics

Fig. 2

From: The various clinical spectra of juvenile xanthogranuloma: imaging for two case reports and review of the literature

Fig. 2

Histological appearance. Skin biopsy specimen from lesion on back. a (HE × 4) shows nodular to diffuse infiltrate of dermis and subcutis, b (HE × 100) monomorphous vacuolated macrophages without significant atypia or atypical mitoses, sparse presence of eosinophils and sparing of papillary and periadnexal dermis (Shapiro variant of xanthogranuloma), c CD163 immunohistochemistry with strong cytoplasmic reactivity (× 100)

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