Prospective audit and feedback on antibiotic use in neonatal intensive care: a retrospective cohort study

BMC Pediatrics

Table 3 Antibiotic spectrum index patterns across indications^a

Characteristic	Pre-ASP		During ASP
	N	Median (IQR)	N	Median (IQR)	p-value
Culture-positive bacteremia	60	7.2 (5.8, 8.5)	32	6.9 (6.3, 7.9)	0.79
Gram-negative organism	23	8.0 (7.5, 10.8)	9	7.8 (6.8, 10.0)	0.66
Gram-positive organism	46	6.5 (5.4, 8.0)	23	6.6 (5.6, 7.5)	0.90
Culture-negative late-onset neonatal sepsis	58	7.7 (6.0, 10.0)	60	8.3 (6.1, 10.0)	0.43

^aPatients who died or were transferred within 3 days of starting antibiotics for culture-positive infection were excluded
ASP antimicrobial stewardship program, IQR interquartile range

ISSN: 1471-2431