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Table 3 Antibiotic spectrum index patterns across indicationsa

From: Prospective audit and feedback on antibiotic use in neonatal intensive care: a retrospective cohort study

Characteristic Pre-ASP During ASP  
  N Median (IQR) N Median (IQR) p-value
Culture-positive bacteremia 60 7.2 (5.8, 8.5) 32 6.9 (6.3, 7.9) 0.79
 Gram-negative organism 23 8.0 (7.5, 10.8) 9 7.8 (6.8, 10.0) 0.66
 Gram-positive organism 46 6.5 (5.4, 8.0) 23 6.6 (5.6, 7.5) 0.90
Culture-negative late-onset neonatal sepsis 58 7.7 (6.0, 10.0) 60 8.3 (6.1, 10.0) 0.43
  1. aPatients who died or were transferred within 3 days of starting antibiotics for culture-positive infection were excluded
  2. ASP antimicrobial stewardship program, IQR interquartile range