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Table 4 Causes of hospitalization

From: Impact of birthweight on health-care utilization during early childhood – a birth cohort study

 

VLBW

N [%]

LBW

N [%]

Reference Group

N [%]

RRa VLBW vs. NBW

RRa LBW vs. NBW

First YOL

Cardiorespiratory system

Acute upper respiratory infections (J00-J06)

43 [4.7]

142 [2.8]

1603 [1.8]

2.6 [1.58,4.28]

1.57 [1.18,2.09]

Influenza and pneumonia (J09-J18)

50 [5.4]

138 [2.7]

1318 [1.5]

3.68 [2.32,5.84]

1.86 [1.39,2.48]

Other acute lower respiratory infections (J20-J22)

115 [12.5]

310 [6.1]

2790 [3.1]

4 [2.98,5.36]

1.97 [1.63,2.38]

Congenital malformations of the circulatory system (Q20-Q28)

10 [1.1]

38 [.8]

211 [.2]

4.6 [1.59,13.26]

3.19 [1.79,5.69]

Symptoms and signs involving the circulatory and respiratory systems (R00-R09)

88 [9.6]

173 [3.4]

897 [1]

9.52 [6.7,13.52]

3.42 [2.61,4.47]

Central nervous system

Episodic and paroxysmal disorders (G40-G47)

40 [4.3]

60 [1.2]

298 [.3]

13.02 [7.56,22.42]

3.57 [2.24,5.67]

Other disorders of the nervous system (G90-G99)

14 [1.5]

15 [.3]

68 [.1]

19.97 [7.65,52.14]

3.91 [1.53,9.98]

Gastrointestinal system

Intestinal infectious diseases (A00-A09)

60 [6.5]

334 [6.6]

3594 [4]

1.62 [1.07,2.45]

1.65 [1.37,1.98]

Hernia (K40-K46)

102 [11.1]

197 [3.9]

698 [.8]

14.18 [10.18,19.75]

5 [3.85,6.49]

Symptoms and signs involving the digestive system and abdomen (R10-R19)

15 [1.6]

69 [1.4]

551 [.6]

2.64 [1.12,6.21]

2.22 [1.46,3.37]

Prematurity-related problems

Respiratory and cardiovascular disorders specific to the perinatal period (P20-P29)

102 [11.1]

147 [2.9]

286 [.3]

34.6 [24.06,49.77]

9.11 [6.54,12.67]

Other disorders originating in the perinatal period (P90-P96)

11 [1.2]

48 [1]

467 [.5]

2.29 [.84,6.2]

1.82 [1.11,2.99]

Others

Benign neoplasms (D10-D36)

17 [1.8]

46 [.9]

252 [.3]

6.54 [2.89,14.82]

3.23 [1.91,5.47]

General symptoms and signs (R50-R69)

38 [4.1]

135 [2.7]

1034 [1.2]

3.57 [2.09,6.07]

2.31 [1.72,3.11]

Injuries to the head (S00-S09)

17 [1.8]

146 [2.9]

2774 [3.1]

.59 [.27,1.31]

.93 [.71,1.23]

Persons with potential health hazards related to communicable diseases (Z20-Z29)b

183 [19.9]

64 [1.3]

39 [0]

455.24 [257.45,805]

29.08 [14.93,56.64]

Second YOL

Cardiorespiratory system

Acute upper respiratory infections (J00-J06)

30 [4]

138 [3.4]

1768 [2.5]

1.62 [.93,2.83]

1.38 [1.05,1.8]

Influenza and pneumonia (J09-J18)

32 [4.3]

122 [3]

1429 [2]

2.14 [1.25,3.68]

1.51 [1.13,2.01]

Other acute lower respiratory infections (J20-J22)

66 [8.9]

156 [3.9]

1488 [2.1]

4.24 [2.93,6.15]

1.85 [1.43,2.39]

Central nervous system

Episodic and paroxysmal disorders (G40-G47)

11 [1.5]

29 [.7]

192 [.3]

5.48 [2.12,14.19]

2.67 [1.44,4.93]

Gastrointestinal system

Intestinal infectious diseases (A00-A09)

50 [6.7]

218 [5.4]

2983 [4.2]

1.6 [1.05,2.45]

1.29 [1.05,1.59]

Others

Diseases of middle ear and mastoid (H65-H75)

10 [1.3]

32 [.8]

469 [.7]

2.04 [.76,5.44]

1.21 [.69,2.11]

Congenital malformations of genital organs (Q50-Q56)

24 [3.2]

32 [.8]

269 [.4]

8.54 [4.46,16.32]

2.1 [1.18,3.74]

General symptoms and signs (R50-R69)

14 [1.9]

45 [1.1]

527 [.7]

2.54 [1.11,5.82]

1.51 [.94,2.43]

Injuries to the head (S00-S09)

23 [3.1]

106 [2.6]

1877 [2.6]

1.17 [.62,2.22]

1 [.74,1.35]

Third YOL

Cardiorespiratory system

Acute upper respiratory infections (J00-J06)

19 [3.2]

63 [2.1]

757 [1.4]

2.33 [1.18,4.59]

1.49 [1.02,2.19]

Influenza and pneumonia (J09-J18)

34 [5.8]

70 [2.3]

724 [1.3]

4.36 [2.63,7.23]

1.73 [1.2,2.5]

Other acute lower respiratory infections (J20-J22)

21 [3.6]

49 [1.6]

619 [1.1]

3.15 [1.65,6.01]

1.42 [.92,2.2]

Other diseases of upper respiratory tract (J30-J39)

16 [2.7]

78 [2.6]

1271 [2.3]

1.17 [.56,2.44]

1.1 [.78,1.55]

Gastrointestinal system

Intestinal infectious diseases (A00-A09)

23 [3.9]

82 [2.7]

1130 [2.1]

1.89 [1.02,3.49]

1.3 [.93,1.82]

Others

Congenital malformations of genital organs (Q50-Q56)

16 [2.7]

21 [.7]

190 [.3]

7.82 [3.65,16.76]

1.98 [1,3.91]

General symptoms and signs (R50-R69)

10 [1.7]

24 [.8]

223 [.4]

4.16 [1.61,10.78]

1.93 [1.02,3.64]

Injuries to the head (S00-S09)

11 [1.9]

57 [1.9]

965 [1.8]

1.06 [.43,2.58]

1.06 [.71,1.58]

Fourth YOL

Cardiorespiratory system

Acute upper respiratory infections (J00-J06)

11 [2.7]

24 [1.1]

342 [.9]

3.08 [1.38,6.87]

1.26 [.72,2.2]

Influenza and pneumonia (J09-J18)

19 [4.6]

39 [1.8]

308 [.8]

5.91 [3.2,10.91]

2.27 [1.45,3.56]

Other diseases of upper respiratory tract (J30-J39)

13 [3.2]

77 [3.5]

1003 [2.5]

1.24 [.6,2.57]

1.38 [1.01,1.88]

  1. aBonferroni-correction of significance level (α = 0.05) due to distinct number of comparisons: 1.YOL α = 0.001, 2.YOL: α = 0.002, 3.YOL: α = 0.003, 4.YOL: α = 0.008
  2. Shown are numbers [N] and relative percentage [%] of infants that had been hospitalized at least once due to the depicted ICD blocks within respective year of life. All ICD blocks with at least 10 children in each weight group were chosen; all blocks of chapter XXI of ICD-10-GM were excluded, except from block Z20-Z29, which contains vaccination(b). Risk ratios are shown with Bonferroni corrected confidence intervals. Note: Due to decreasing overall case numbers there are less ICD blocks with at least 10 children with increasing YOL