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Table 3 Prevalence of endocrine and metabolic alterations in children and adolescents with SCD

From: Endocrine and metabolic complications in children and adolescents with Sickle Cell Disease: an Italian cohort study

Endocrine/metabolic complications

N°/52

%

M/F

SS/SC

Vitamin D insufficiency (10–30 ng/ml)

33

63.5%

16/17

24/9

Vitamin D deficiency (< 10 ng/ml)

11

21.2%

7/4

7/4

GHD

2

3.8%

2/0

2/0

Subclinical hypothyroidism

2

3.8%

1/1

2/0

Hypergonadotropinic hypogonadism

1

1.9%

1/0

1/0

Ovarian insufficiency

1

1.9%

0/1

1/0

Insulin resistance

6

11.5%

2/4

4/2

  1. Abbreviations: GHD growth deficiency hormone