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Table 1 Characteristics of the 666 children and adolescents enrolled in the EnPRISE study, 2015, Senegal

From: High level of treatment failure and drug resistance to first-line antiretroviral therapies among HIV-infected children receiving decentralized care in Senegal

Characteristics

n

n

%

%

N

666

   

Gender (n = 666)

 Girl

328

 

49%

 

Age (n = 666)

 < 5 years

159

 

24%

 

 5–10 years

253

 

38%

 

 10–14 years

213

 

32%

 

 > 14 years

41

 

6%

 

Education (n = 666)

 No formal education

235

 

35%

 

 Educated

431

 

65%

 

  Primary

 

255

 

59%

  Arabic-Koranica

 

99

 

23%

  Secondary

 

47

 

11%

  Unavailable

 

30

 

7%

Family status (n = 666)

 Both parents alive

273

 

41%

 

 One parent alive

292

 

44%

 

 Orphans of both parents

101

 

15%

 

Testing of siblings (n = 666)

 No siblings

82

 

13%

 

 Siblings

485

 

72%

 

  No one tested

135

 

28%

 

  At least one tested

140

 

29%

 

  All tested

210

 

43%

 

 Unavailable

99

 

15%

 

Type of facility b (n = 666)

 Health Center

322

 

48%

 

 Level-I Hospital

141

 

21%

 

 Level-II Hospital

196

 

30%

 

 Level-III Hospital

7

 

1%

 

Responsible for treatment (n = 666)

 General practitioner

432

 

65%

 

 Pediatrician

234

 

35%

 

Disclosure (n = 666)

 Children < 8 years (not notified)

243

 

37%

 

 Age ≥ 8 years

300

 

45%

 

  Notified of status

42

 

14%

 

  Not notified of status

258

 

86%

 

 Unavailable

123

 

18%

 

Gateway to care c (n = 666)

 Care

347

 

52%

 

 Familial

270

 

40%

 

 PMTCT

12

 

2%

 

 Unavailable

37

 

6%

 

Regularity of follow-up d (n = 666)

 Regular

482

 

72%

 

 Not regular

128

 

19%

 

 Unavailable

56

 

9%

 

Prolonged treatment interruptions e (n=666)

 Yes

75

 

11%

 

 No

586

 

88%

 

 Unavailable

5

 

1%

 

Nutritional status f (n = 666)

 Normal

393

 

59%

 

 Moderate acute malnutrition (MAM)

95

 

14%

 

 Severe acute malnutrition (SAM)

87

 

13%

 

 Overweight

28

 

4%

 

 Unavailable

63

 

10%

 

Exposure to PMTCT (n = 666)

 Yes

45

 

7%

 

 No

468

 

70%

 

 Age < 10 years

412

 

88%

 

 Age ≥ 10 years

56

 

12%

 

 Unavailable

153

 

23%

 

ART Therapy (n = 666)

 Children untreated

65

 

10%

 

 Children treated

601

 

90%

 

Viral load (n = 666)

 Treatment ≤6 months

103

 

17%

 

 Treatment > 6 months

498

 

83%

 

 < 1000 cp/mL

 

178

 

36%

 ≥1000 cp/mL

 

320

 

64%

Duration of follow-up (treatment > 6 months n = 498)

 6–12 months

110

 

22%

 

 13–24 months

113

 

23%

 

 >  24 months

275

 

55%

 

Treatment regimen (treatment > 6 months n = 498) g

 AZT + 3TC + NVP/EFV

425

 

85%

 

 Other NRTI+NNRTI combinations

37

 

8%

 

 Combination with PI

36

 

7%

 

Adherence h (all children on treatment n = 601)

 Good

372

 

61%

 

 Average

81

 

13%

 

 Poor

61

 

10%

 

 Unavailable

87

 

14%

 
  1. aFranco-Arabic/Koranic schools based on the study of the Koran and Arabic language
  2. bLevel-I Hospital, departmental level; Level-II Hospital, regional level; Level-III Hospital, national level
  3. cGateway to care: place of first consultation leading to HIV testing
  4. dRegularity of follow-up: quarterly
  5. eProlonged treatment interruptions: greater than one month
  6. fNutritional status: based on WHO criteria
  7. gTreatment regimen
  8. hAdherence: estimated by physician