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Table 6 Healthcare resource utilization and costs during one year after birth

From: Prevalence and burden of illness of treated hemolytic neonatal hyperbilirubinemia in a privately insured population in the United States

 

Treated hemolytic NHB cohort

(N = 765)

Matched non-NHB cohort

(N = 765)

p-value1

All-cause healthcare resource use

 Inpatient

  Readmission within 30-days after birth, n (%)

60 (7.8)

14 (1.8)

< 0.001

  Inpatient admission from 31 days to one year after birth

36 (4.7)

24 (3.1)

0.109

 Emergency room visits, n (%)

138 (18.0)

125 (16.3)

0.378

  Number of visits, mean (SD)

1.3 (0.72)

1.2 (0.50)

0.690

 Physician office visits, n (%)

763 (99.7)

745 (97.4)

< 0.001

  Number of visits, mean (SD)

12.2 (5.44)

10.7 (4.92)

< 0.001

 Other outpatient visits2, n (%)

763 (99.7)

736 (96.2)

< 0.001

  Number of visits, mean (SD)

11.3 (7.25)

8.3 (7.28)

< 0.001

 Prescription fills, n (%)

533 (69.7)

486 (63.5)

0.009

  Number of fills, mean (SD)

4.3 (4.36)

3.9 (3.94)

0.140

All-cause healthcare costs, mean (SD), 2017 USD

 Newborns

  Medical costs

$21,407 ($60,808)

$12,784 ($71,669)

< 0.001

   Inpatient (including birth hospitalization)

$16,679 ($58,723)

$8865 ($70,060)

< 0.001

   Emergency department

$279 ($850)

$235 ($749)

0.199

   Physician office visits

$1,443 ($847)

$1,248 ($864)

< 0.001

   Other outpatient visits

$3,006 ($4,096)

$2,436 ($3,712)

< 0.001

  Pharmacy costs

$149 ($359)

$202 ($1494)

0.038

Total newborn medical and pharmacy costs

$21,556 ($60,823)

$12,986 ($72,164)

< 0.001

Incremental all-cause healthcare costs

 Treated hemolytic NHB newborn incremental costs

$8,570 ($82,379)

 Mother’s delivery incremental costs3

$813 ($12,922)

Total incremental costs

$9,383 ($84,478)

  1. NHB neonatal hyperbilirubinemia, SD standard deviation
  2. 1p-values calculated using McNemar test for binary variables and Wilcoxon signed-rank test for continuous variables
  3. 2Other outpatient visits included durable medical equipment, imaging, medication & related services, procedures, physician other services, lab tests and occupational, physical or speech therapy
  4. 3A newborn’s care and treatment could be billed to his/her mother’s plan during birth hospitalization; mother’s incremental costs of delivery hospitalization were included