Treated hemolytic NHB cohort (N = 1373) | Matched non-NHB cohort (N = 1373) | p-value1 | |
---|---|---|---|
All-cause healthcare resource use | |||
Inpatient | |||
Birth hospitalization LOS, mean (SD) | 4.5 (6.06) | 3.0 (5.74) | < 0.001 |
NICU admission during birth hospitalization, n (%) | 1,134 (82.6) | 961 (70.0) | < 0.001 |
NICU Level 1 | 903 (65.8) | 910 (66.3) | 0.713 |
NICU Level 2 | 215 (15.7) | 33 (2.4) | < 0.001 |
NICU Level 3 | 218 (15.9) | 38 (2.8) | < 0.001 |
NICU Level 4 | 146 (10.6) | 35 (2.5) | < 0.001 |
Readmission within 30-days after birth, n (%) | 119 (8.7) | 23 (1.7) | < 0.001 |
LOS, mean (SD) | 2.4 (2.62) | 1.7 (1.34) | 0.033 |
Emergency room visits, n (%) | 23 (1.7) | 19 (1.4) | 0.537 |
Number of visits, mean (SD) | 1.0 (0.21) | 1.1 (0.23) | 0.919 |
Physician office visits, n (%) | 1,247 (90.8) | 1,134 (82.6) | < 0.001 |
Number of visits, mean (SD) | 2.8 (1.49) | 2.2 (1.15) | < 0.001 |
Other outpatient visits2, n (%) | 1,001 (72.9) | 427 (31.1) | < 0.001 |
Number of visits, mean (SD) | 3.8 (3.29) | 1.5 (1.26) | < 0.001 |
Prescription fills, n (%) | 86 (6.3) | 83 (6.0) | 0.811 |
Number of fills, mean (SD) | 1.2 (0.43) | 1.1 (0.36) | 0.533 |
All-cause healthcare costs, mean (SD), 2017 USD | |||
Medical costs | $14,403 ($43,918) | $5,524 ($50,078) | < 0.001 |
Inpatient (including birth hospitalization) | $13,794 ($43,949) | $5,216 ($50,083) | < 0.001 |
Birth hospitalization | $12,616 ($42,475) | $5,155 ($50,080) | < 0.001 |
Readmission during 30 days after birth3 | $13,593 ($34,524) | $3,638 ($5685) | < 0.001 |
Emergency department | $20 ($187) | $17 ($169) | 0.636 |
Physician office visit | $313 ($258) | $224 ($203) | < 0.001 |
Other outpatient visits | $276 ($651) | $67 ($289) | < 0.001 |
Pharmacy costs | $2 ($12) | $2 ($28) | 0.923 |
Total medical and pharmacy costs | $14,405 ($43,918) | $5,527 ($50,079) | < 0.001 |
Incremental all-cause healthcare costs | |||
Treated hemolytic NHB newborn incremental costs | $8,878 ($59,943) | ||
Mother’s delivery incremental costs4 | $503 ($19,969) | ||
Total incremental costs | $9,381 ($63,558) |