Skip to main content

Table 5 Healthcare resource utilization and costs during 30 days after birth

From: Prevalence and burden of illness of treated hemolytic neonatal hyperbilirubinemia in a privately insured population in the United States

 

Treated hemolytic NHB cohort

(N = 1373)

Matched non-NHB cohort

(N = 1373)

p-value1

All-cause healthcare resource use

 Inpatient

  Birth hospitalization LOS, mean (SD)

4.5 (6.06)

3.0 (5.74)

< 0.001

  NICU admission during birth hospitalization, n (%)

1,134 (82.6)

961 (70.0)

< 0.001

   NICU Level 1

903 (65.8)

910 (66.3)

0.713

   NICU Level 2

215 (15.7)

33 (2.4)

< 0.001

   NICU Level 3

218 (15.9)

38 (2.8)

< 0.001

   NICU Level 4

146 (10.6)

35 (2.5)

< 0.001

  Readmission within 30-days after birth, n (%)

119 (8.7)

23 (1.7)

< 0.001

  LOS, mean (SD)

2.4 (2.62)

1.7 (1.34)

0.033

 Emergency room visits, n (%)

23 (1.7)

19 (1.4)

0.537

  Number of visits, mean (SD)

1.0 (0.21)

1.1 (0.23)

0.919

 Physician office visits, n (%)

1,247 (90.8)

1,134 (82.6)

< 0.001

  Number of visits, mean (SD)

2.8 (1.49)

2.2 (1.15)

< 0.001

 Other outpatient visits2, n (%)

1,001 (72.9)

427 (31.1)

< 0.001

  Number of visits, mean (SD)

3.8 (3.29)

1.5 (1.26)

< 0.001

 Prescription fills, n (%)

86 (6.3)

83 (6.0)

0.811

  Number of fills, mean (SD)

1.2 (0.43)

1.1 (0.36)

0.533

All-cause healthcare costs, mean (SD), 2017 USD

 Medical costs

$14,403 ($43,918)

$5,524 ($50,078)

< 0.001

  Inpatient (including birth hospitalization)

$13,794 ($43,949)

$5,216 ($50,083)

< 0.001

   Birth hospitalization

$12,616 ($42,475)

$5,155 ($50,080)

< 0.001

   Readmission during 30 days after birth3

$13,593 ($34,524)

$3,638 ($5685)

< 0.001

  Emergency department

$20 ($187)

$17 ($169)

0.636

  Physician office visit

$313 ($258)

$224 ($203)

< 0.001

  Other outpatient visits

$276 ($651)

$67 ($289)

< 0.001

 Pharmacy costs

$2 ($12)

$2 ($28)

0.923

Total medical and pharmacy costs

$14,405 ($43,918)

$5,527 ($50,079)

< 0.001

Incremental all-cause healthcare costs

 Treated hemolytic NHB newborn incremental costs

$8,878 ($59,943)

 Mother’s delivery incremental costs4

$503 ($19,969)

Total incremental costs

$9,381 ($63,558)

  1. NHB neonatal hyperbilirubinemia, SD standard deviation, LOS length of stay
  2. 1p-values calculated using McNemar test for binary variables and Wilcoxon signed-rank test for continuous variables
  3. 2Other outpatient visits included durable medical equipment, imaging, medication & related services, procedures, physician other services, tests and occupational, physical or speech therapy
  4. 3Readmission costs calculated among those who had readmission during the first 30 days after birth, including 119 newborns in treated hemolytic NHB cohort and 23 newborns in matched non-NHB cohort
  5. 4A newborn’s care and treatment could be billed to his/her mother’s plan during birth hospitalization; mother’s incremental costs of delivery hospitalization were included