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Table 5 Risk factors of blood stream infections among children in North-western Tanzania

From: Deciphering risk factors for blood stream infections, bacteria species and antimicrobial resistance profiles among children under five years of age in North-Western Tanzania: a multicentre study in a cascade of referral health care system

Variable

 

BSIs (n, %)

Univariate OR (95%CI)

p-value

Multivariate OR (95%CI)

p-value

Hospital

NDH & SDDH (218)

18 (8.3)

1

   

SRRH (218)

14 (6.4)

0.76 (0.37–1.57)

0.464

0.90 (0.43–1.90)

0.917

BMC (514)

103 (20.0)

2.78 (1.64–4.72)

< 0.001

2.01 (1.08–3.74)

0.028

Sex

Boys (558)

80 (14.3)

1

   

Girls (392)

55 (14.0)

0.97 (0.67–1.41)

0.894

  

Age category

13–60 months (395)

35 (8.9)

1

   

2–12 months (209)

12 (5.7)

0.63 (0.32–1.23)

0.177

0.59 (0.30–1.17)

0.128

≤1 month (346)

88 (25.4)

3.51 (2.30–5.36)

< 0.001

1.93 (1.07–3.48)

0.030

Weight (kg)

Normal (539)

85 (15.8)

1

   

Underweight (373)

49 (13.1)

0.81 (0.55–1.18)

0.270

  

Overweight (38)

1 (2.6)

0.14 (0.02–1.07)

0.058

  

Residence

Rural (315)

39 (12.4)

1

   

Urban (635)

96 (15.1)

1.26 (0.85–1.88)

0.256

  

Mwanza city

No (313)

41 (13.1)

1

   

Yes (637)

94 (14.8)

1.15 (0.78–1.71)

0.492

  

Current antibiotic use

No (545)

66 (12.1)

1

   

Yes (405)

69 (17.0)

1.49 (1.03–2.15)

0.032

1.42 (0.97–2.08)

0.069

Previous admission*

No (525)

39 (7.4)

1

   

Yes (79)

8 (10.1)

1.40 (0.63–3.13)

0.406

  

Intravenous line

No (254)

27 (10.6)

1

   

Yes (696)

108 (15.5)

1.54 (0.99–2.42)

0.058

  

Urinary catheter

No (930)

132 (14.2)

1

   

Yes (20)

3 (15.0)

1.07 (0.31–3.69)

0.919

  

Co-morbidities**

No (558)

85 (15.2)

1

   

Yes (392)

50 (12.8)

0.81 (0.56–1.18)

0.282

  

Prematurity

No (900)

121 (13.4)

1

   

Yes (50)

14 (28.0)

2.50 (1.31–4.78)

0.005

1.15 (0.58–2.25)

0.691

Malnutrition

No (825)

126 (15.3)

1

   

Yes (125)

9 (7.2)

0.43 (0.21–0.87)

0.019

0.52 (0.22–1.20)

0.126

HIV

Negative (913)

129 (14.1)

1

   

Positive (37)

6 (16.2)

1.18 (0.48–2.88)

0.722

  

SCD

No (921)

132 (14.3)

1

   

Yes (29)

3 (10.3)

0.69 (0.21–2.31)

0.547

  
  1. BMC Bugando Medical Center, SRRH Sekou Toure Regional Referral Hospital, NDH Nyamagana District Hospital, SDDH Sengerema District Designated Hospital:* In the past three months (excluding current admission); **Malnutrition (n = 105), Respiratory tract infections (n = 86), Prematurity (n = 50), Congenital anomalies (n = 36: congenital heart diseases, neural tube defects, hydrocephalus and others), Anemia (n = 31), SCD: Sickle cell disease (n = 26),HIV (n = 19), Skin and soft tissue infections (n = 8); Necrotising enterocolitis (n = 3); Amoebiasis (n = 2); Burn injury (n = 2); Rheumatic heart diseases (n = 2); Cerebral malaria (n = 1); Spinal injury (n = 1); Malnutrition and HIV (n = 17); Malnutrition and sickle cell disease (n = 3); Premature and HIV (n = 1)