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Table 2 Olaparib administration doses (mg) per BSA

From: Phase I clinical study of oral olaparib in pediatric patients with refractory solid tumors: study protocol

BSA (m2) Olaparib administration doses (mg b.i.d.)
1st dose
(62.5 mg/m2)
2nd dose
(125 mg/m2)
3rd dose
(187.5 mg/m2)
0.40 ≤ BSA < 0.50 25 50 75
0.50 ≤ BSA < 0.60 25 50 75
0.60 ≤ BSA < 0.70 25 75 100
0.70 ≤ BSA < 0.80 25 75 125
0.80 ≤ BSA < 0. 90 50 100 150
0.90 ≤ BSA < 1.00 50 100 150
1.00 ≤ BSA < 1.10 50 125 175
1.10 ≤ BSA < 1.20 50 125 200
1.20 ≤ BSA < 1.30 75 150 225
1.30 ≤ BSA < 1.40 75 150 225
1.40 ≤ BSA < 1.50 75 175 250
1.50 ≤ BSA < 1.60 75 175 275
1.60 ≤ BSA 100 200 300
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