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Table 4 Risk of adverse neuro-developmental outcomes in children < 10 years of age born with birth weight < 2000 g compared to those born with normal birth weight (≥2500 g)

From: Cognitive and motor outcomes in children born low birth weight: a systematic review and meta-analysis of studies from South Asia

Outcomes No. of studies No. of subjects Age range Effect size (95% CI) I 2 Statistic
Cognitive score 4 479 < 10 years WMD −7.23 (−9.20; −5.26) 8.7%
3 407 < 10 years RR 3.59 (1.55; 8.32)a 0.0%
Motor score 2 152 < 10 years WMD −6.45 (−9.64; −3.27) 0.0%
2 135 < 10 years RR 3.72 (1.32; 10.54)b 0.0%
  1. aRepresents the risk of having “low cognitive performance” defined as mental quotient of < 85 or IQ score ≤ 25th percentile
  2. bDenotes the risk of having “low motor performance” defined as either presence of signs of motor dysfunction on clinical examination or motor quotient of < 85