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Table 2 Baseline characteristics of HIV infected children in HIV clinic at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia from April 1 to May 15, 2018 (n = 318).Baseline characteristics of

From: Predictors of treatment failure, time to switch and reasons for switching to second line antiretroviral therapy in HIV infected children receiving first line anti-retroviral therapy at a Tertiary Care Hospital in Ethiopia

Variables

N (%)

Age years (at the time of cART initiation)

  ≤ 11 months

91(28.6)

 12 to 34 months

63(19.8)

 35–59 months

52(16.4)

  ≥ 60 months

112(35.2)

Initial HAART Regimen

 D4T-3TC-NVP

59(18.5)

 D4T-3TC-EFV

17(5.3)

 AZT-3TC-NVP

103(32.3)

 AZT-3TC-EFV

53(16.6)

 TDF-3TC-EFV

26(8.1)

 AZT-3TC-LPV/r

10(3.1)

 ABC-3TC-LPV/r

6(1.5)

 ABC-3TC-EFV

23(7.2)

 D4T-3TC-LPV/r

21(6.6)

Initial cART dosing preparations

 One loose

94(29.6)

 Three loose

81(25.5)

 Fixed

143(45)

PMTCT Service

 Present

21(6.6)

 None

237(74.5)

 Unknown

60(18.8)

Infant ART Prophylaxis

 Yes

37(11.6)

 No

235(73.8)

 Unknown

56(17.6)

Baseline Immunosuppression level

 Not Significant Immunosuppression (≥  500 or > 25%)

3(0.94)

 Mild Immunosuppression (350–499 or 20–24%)

23(7.2)

 Advanced Immunosuppression (200–349 or 15–19%)

137(43.08)

 Severe Immunosuppression (< 200 or < 15%)

155(48.74)

Base line WHO staging

 Stage 1

26(8.17)

 Stage 2

109(34.3)

 Stage 3

155(48.7)

 Stage 4

28(8.8)