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Table 1 Clinical characteristics of subjects with and without pulmonary hypertension in infants with moderate/severe BPD

From: Developmental outcomes of preterm infants with bronchopulmonary dysplasia-associated pulmonary hypertension at 18–24 months of corrected age

 

PH

Non-PH

P-values

(n = 20)

(n = 61)

Gestational age, weeks

25.3 ± 1.4

25.8 ± 1.1

0.126

Birth weight, g

710.1 ± 183.6

758.6 ± 159.1

0.257

Birth weight < 10th percentile for age, n (%)

5 (25.0)

9 (14.8)

0.317

Multiple birth, n (%)

3 (15.0)

35 (57.4)

0.002

Cesarean section, n (%)

13 (65.0)

35 (57.4)

0.608

Perinatal steroids administration, n (%)

15 (75.0)

42 (68.9)

0.601

Chorioamnionitis, n (%)

12 (60.0)

25 (41.0)

0.138

Preeclampsia, n (%)

3 (15.0)

6 (9.8)

0.750

Oligohydramnios, n (%)

4 (20.0)

3 (5.1)

0.059

RDS, n (%)

16 (80.0)

45 (73.8)

0.767

Treated PDA, n (%)

16 (80.0)

47 (77.0)

1.000

BPD, n (%)

  

<  0.001

 Moderate

3 (15.0)

38 (62.3)

 

 Severe

17 (85.0)

23 (37.7)

 

Culture proven sepsis, n (%)

11 (55.0)

15 (24.6)

0.011

ROP operation, n (%)

7 (35.0)

34 (55.7)

0.128

NEC operation, n (%)

6 (30.0)

6 (9.8)

0.063

BPD steroid, n (%)

5 (25.0)

6 (9.8)

0.128

Length of stay, days

111 (82–268)

103 (71–163)

0.044

  1. Data are presented as mean ± SD, median and range, or rate
  2. PH pulmonary hypertension, RDS respiratory distress syndrome, PDA patent ductus arteriosus, BPD bronchopulmonary dysplasia, ROP retinopathy of prematurity, NEC necrotizing enterocolitis