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Table 2 Medications in the three groups

From: Evaluation of systemic inflammatory response syndrome-negative sepsis from a Chinese regional pediatric network

  Sepsisc SSc SNS p
Cases, n 1377 153d 76  
Antimicrobial therapy
 pre-hospital, n (%) 1054 (76.5) 123 (80.9) 65 (86.7) 0.101
 during, n (%) 1354 (98.3) 148 (96.7) 76 (100.0) 0.177
 within 2 h, n (%) 1243 (91.7) 132 (88.6) 69 (90.8) 0.422
 time, days mean ± SD 8.4 ± 4.6 10.3 ± 7.9a 12.4 ± 5.5ab 0.000
Other therapy
 GS, n (%) 500 (36.4) 120 (79.5)a 57 (75.0)a 0.000
 VA, n (%) 23 (0.5) 103 (67.3)a 46 (60.5)a 0.000
 IA, n (%) 3 (0.2) 92 (60.1)a 63 (82.9)ab 0.000
 Sedatives, n (%) 100 (7.3) 109 (71.2)a 59 (77.6)a 0.000
 IVIG, n (%) 52 (3.8) 49 (32.2)a 19 (25.0)a 0.000
  1. Group definition: Sepsis, sepsis; SS, severe sepsis; SNS, SIRS-negative sepsis
  2. Definition of abbreviations: pre-hospital, antimicrobial therapy was started prior to admission; during, antimicrobial therapy was given during hospitalization; within 2 h, intravenous antimicrobial therapy was started within 2 h of recognizing sepsis; time, the entire period of antimicrobial treatment; GS, glucocorticosteroids; VA, vasoactive agents; IA, inotropes; IVIG, intravenous immunoglobulin
  3. Statistical analysis: a p < 0.01 vs, S; b p < 0.01 vs, SS
  4. cValues are taken from reference [15]; dNumbers include 32 septic shock