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Table 1 Baseline data and clinical characteristics of the patients at study entry and outcome

From: Evaluation of systemic inflammatory response syndrome-negative sepsis from a Chinese regional pediatric network

Variables Sepsisa SSa SNS p
Case, n 1377 153b 76  
Age, year, mean (median) 3.3 (2.0) 1.6 (0.6) 0.7 (0.3) 0.000
Gender, boys (girls), n (n) 904 (473) 95 (58) 50 (26) 0.678
Rural residents, n (%) 843 (61.7) 122 (79.7) 62 (81.6) 0.000
Temperature, mean ± SD, °C 39.0 ± 0.7 38.3 ± 1.4 37.2 ± 0.6 0.000
Underlying diseases, n (%) 55 (4.0) 55 (35.9) 22 (28.9) 0.000
C-reactive protein (CRP) 36.9 ± 55.0 32.5 ± 58.5 6.7 ± 18.5 0.000
Sources of infection, n (%)
 Lower respiratory tract 418 (30.4) 98 (64.0) 68 (89.5) 0.000
 Upper respiratory tract 414 (30.1) 0 0 0.000
 Central nervous system 145 (10.5) 20 (13.1) 5 (6.6) 0.000
 Unknown 265 (19.2) 13 (7.4) 1 (1.3) 0.000
 Gastrointestinal system 67 (4.9) 17 (11.1) 1 (1.3) 0.000
 Blood stream 49 (3.6) 4 (2.6) 1 (1.3) 0.000
 Soft tissue 18 (1.3) 1 (0.7) 0 0.000
Mental status, n (%)
 Irritability 21 (1.5) 34 (22.2) 21 (27.6) 0.000
 Convulsions 147 (10.7) 32 (20.9) 5 (6.6) 0.000
 Twitches 6 (0.4) 3 (2.0) 0 0.000
 Decreased level of consciousness 275 (20.0) 121 (79.1) 42 (55.3) 0.000
Organ or system dysfunction, n (%)
 Cardiovascular 0 32 (20.9) 42 (55.3) 0.000
 Respiratory 0 58 (37.9) 2 (2.6) 0.000
 Coagulation 0 8 (5.2) 1 (1.3) 0.000
 Electrolyte imbalance 15 (1.1) 22 (14.4) 3 (3.9) 0.000
 MODS 0 27 (17.6) 0  
Deaths, n (%) 1 (0.1) 53 (34.6) 1 (1.3) 0.000
  1. Group definitions: Sepsis, sepsis; SS, severe sepsis; SNS, SIRS-negative sepsis
  2. Definition of abbreviations: MODS, multiple organ dysfunction syndrome
  3. aValues are taken from reference [15]; bNumbers include 32 septic shock