Fig. 3

a Axial T2-weighted brain MRI. At 14 months of age (upper panels), abnormal areas of white matter were localized and remained around the lateral ventricle (arrow) and parietal lobes (round circles) in comparison to the findings at 1.5 months of age (see Fig. 1). The arrowhead indicates a periventricular cyst around the anterior horn of the right lateral ventricle. b At 3 years of age (middle panels), the abnormal white matter areas on T2-weighted images decreased further (arrow and circle). The periventricular cyst around the anterior horn of the right lateral ventricle was unchanged (arrowhead). c At 9 years of age (lower panels), a decreased volume of cerebral white matter was observed, but the abnormal areas of white matter had mostly disappeared, except for spotty signals in the parietal and occipital lobes (circles)