YKL-40 levels are associated with disease severity and prognosis of viral pneumonia, but not available in bacterial pneumonia in children

Table 2 Logistics regression analysis for the factors associated with the prognosis of pneumonia

	OR	95% CI	P value
Rate of sepsis: Yes (45, 16.1%), No (235, 83.9%)
Age (continuous variable)	1.21	0.85,1.54	0.652
Previous pneumonia(binary variable)	0.92	0.85,1.24	0.096
Decreased extent of YKL-40 (classified variable)	2.84	2.16,3.65	0.008
Infectious type (unordered variable)	1.23	0.97,1.48	0.078
Procalcitonin (continuous variable)	1.12	1.03,1.22	0.044
Mechanical ventilation rate: Yes (31, 11.1%), No (249, 88.9%)
Age (continuous variable)	1.235	1.156,1.366	0.023
Previous pneumonia (binary variable)	2.02	1.68,2.26	0.034
Decreased extent of YKL-40 (classified variable)	1.69	1.26,2.08	0.012
Infectious type (unordered variable)	1.63	1.21,2.27	0.028
Procalcitonin (continuous variable)	1.021	0.916,1.148	0.189
Intensive Care Unit admission rate: Yes (36, 12.9%), No (244, 87.1%)
Age (continuous variable)	1.23	1.12,1.51	0.041
Previous pneumonia (binary variable)	1.21	0.93,1.87	0.267
Decreased extent of YKL-40 (classified variable)	3.21	2.68,4.79	0.016
Infectious type (unordered variable)	1.35	1.21,1.45	0.030
Procalcitonin (continuous variable)	1.09	0.91,1.17	0.526

Data are presented as hazard ratios, representing the relative risk of adverse therapeutic events and poor prognosis. The independent risk factors of mechanical ventilation including the age, infectious type, infections history in the previous and decreased extent of YKL-40. The age, infectious type, decreased extent of YKL-40 not associated with the increased rate of mechanical ventilation but also considered as the independent risk factors of ICU admission

ISSN: 1471-2431