Skip to main content

Table 2 OGTT variables

From: Using neuroimaging to investigate the impact of Mandolean® training in young people with obesity: a pilot randomised controlled trial

Measures (median (IQR)) Mandolean+ group Standard care group Cliff’s delta (C.I.)
Baseline Post-Intervention Mean % difference (C.I.)a Baseline Post-Intervention Mean % difference (C.I.)a (Post-Intervention)
N with VAS ratings 10 10 10 9 9 9  
Fullness rating (0–7 Likert scale)
 Fasting 2.00 (2.00) 3.50 (1.25) 125.93 (−20.02, 271.87) 2.00 (1.50) 3.00 (1.00) 111.11 (32.40, 189.82) 0.21 (− 0.28, 0.62)
 Post glucose load: 30 mins. 2.00 (3.00) 4.50 (2.50) b-70.00 (−173.89, 33.89) 4.00 (2.50) 3.00 (1.00) b-96.25 (− 146.22, − 46.28) b0.27 (−0.24, 0.66)
 60 min 1.50 (2.25) 4.00 (1.00) b − 100.00 (− 248.41, 48.41) 2.00 (1.50) 3.00 (2.00) b − 84.00 (− 189.94, 21.94) b0.46 (− 0.08, 0.79)
 90 min 1.00 (2.00) 5.00 (1.25) b − 112.50 (− 341.02, 116.02) 2.00 (3.50) 4.00 (0.50) b − 33.33 (− 119.02, 52.35) b0.52 (0.02, 0.82)
Hunger rating (0–7 Likert scale)
 Fasting 5.00 (3.50) 1.00 (0.50) −54.71 (−80.57, − 28.85) 4.00 (1.50) 2.00 (2.00) −32.33 (− 66.60, 2.16) 0.46 (− 0.78, 0.05)
 Post glucose load: 30 mins. 4.00 (1.50) 1.00 (1.00) b − 106.25 (− 121.03, − 91.47) 3.00 (2.50) 1.00 (1.00) b 45.24 (− 153.10, 243.58) b0.26 (− 0.30, 0.69)
 60 min 4.50 (2.75) 1.00 (0.25) b − 100.00 (− 153.40, − 46.60) 3.00 (2.00) 1.00 (0.50) b − 58.33 (− 165.44, 4.77) b0.23 (− 0.33, 0.67)
 90 min 4.00 (3.00) 1.00 (1.00) b − 107.14 (− 148.75, − 65.54) 4.00 (2.00) 1.00 (1.00) b − 71.43 (− 184.25, 41.39) b0.31 (− 0.26, 0.71)
Thirst rating (0–7 Likert scale)
 Fasting 3.00 (1.50) 3.00 (2.00) − 7.59 (− 48.69, 33.51) 4.00 (2.00) 2.00 (1.50) −21.85 (−62.00, 18.30) 0.31 (− 0.23, 0.70)
 Post glucose load: 30 mins. 2.00 (1.00) 2.00 (3.00) b − 63.33 (− 114.86, − 11.80) 3.00 (3.00) 4.00 (3.00) b − 17.86 (−155.76, 120.04) b0.58 (− 0.85, − 0.07)
 60 min 3.00 (1.00) 2.50 (2.25) b − 100.00 (− 252.07, 52.07) 2.00 (2.00) 3.00 (1.50) b − 140.48 (− 217.99, − 62.97) b0.26 (− 0.65, 0.25)
 90 min 3.00 (1.50) 2.00 (2.25) b − 33.33 (− 176.76, 110.09) 4.00 (2.00) 2.00 (1.50) b − 66.67 (− 121.02, − 12.31) b0.39 (− 0.77, 0.19)
 N with blood plasma data 5 4 4 5 4 4  
Ghrelin (pg/ml)
 Fasting 9.80 (8.25) 14.00 (9.90) 69.24 (− 38.24, 176.72) 14.30 (15.50) 12.40 (7.50) 10.49 (−99.79, 120.77) 0.63 (− 0.38, 0.95)
 Post glucose load: 30 mins. 8.75 (6.58) 14.40 (5.50) − 105.56 (− 271.44, 60.31) 10.60 (15.30) 13.70 (15.00) 94.21 (− 130.27, 318.69) c0.13 (− 0.67, 0.78)
 60 min 9.30 (8.20) 10.50 (4.20) −13.42 (− 220.46, 193.61) 6.90 (6.80) 13.25 (7.80) −78.25 (− 200.61, 44.11) c0.75 (− 0.97, 0.21)
 90 min 7.60 (9.10) 10.05 (6.60) −7.08 (− 167.01, 152.87) 13.30 (17.95) 10.95 (10.80) −58.32 (− 237.17, 120.52) c0.75 (− 0.97, 0.21)
PYY (pg/ml)
 Fasting 79.30 (40.75) 79.50 (38.60) −2.29 (−19.81, 15.23) 63.40 (50.55) 68.75 (73.3) 4.75 (−21.19, 30.70) 0.25 (− 0.61, 0.84)
 Post glucose load: 30 mins. 81.45 (45.33) 83.65 (30.90) − 174.86 (− 511.86, 162.15) 76.60 (15.95) 82.50 (35.00) −10.98 (− 48.89, 26.93) c0.13 (− 0.80, 0.69)
 60 min 58.20 (28.90) 67.90 (29.70) −32.74 (− 56.14, − 9.34) 63.20 (23.15) 60.10 (32.40) −30.02 (− 264.99, 204.95) c0.25 (− 0.61, 0.84)
 90 min 55.00 (21.75) 62.70 (27.20) −30.77 (− 79.01, 17.46) 59.50 (39.20) 83.45 (48.00) 745.41 (− 1610.16, 3100.98) c0.50 (− 0.92, 0.43)
Glucose
 Fasting 6.00 (1.25) 6.4 (0.5) 1.22 (− 21.47, 23.92) 6.24 (0.25) 6.35 (1.48) 1.97 (−16.98, 20.91) 0.06 (− 0.70, 0.76)
 Post glucose load: 30 mins. 10.00 (3.32) 9.55 (2.35) 7.46 (− 64.99, 79.90) 10.40 (4.95) 9.05 (3.52) −87.53 (− 234.61, 59.54) c0.51 (− 0.43, 0.92)
 60 min 10.30 (5.20) 8.45 (1.60) 19.20 (− 200.77, 239.17) 7.30 (2.30) 7.75 (2.03) −30.16 (− 283.69, 223.36) c0.94 (0.35, 1.00)
 90 min 8.40 (0.95) 8.01 (2.45) −11.83 (− 118.84, 95.18) 8.20 (2.35) 7.3 (2.25) −104.87 (− 367.08, 157.33) c0.38 (− 0.52, 0.88)
  1. aMean % difference within groups: ((Post-Intervention value - Baseline value)/Baseline value)*100
  2. bcalculated on change from baseline scores
  3. ccalculated on % change from baseline scores