Fig. 6
From: Clinical and genetic Rett syndrome variants are defined by stable electrophysiological profiles
Spectral power profiles of epilepsy status groups. All subplots depicting a statistical comparison significant at a p value of < 0.05 are marked with an asterisk (*). a Overall power spectra between 1 Hz and 40 Hz for No Epilepsy (n = 18, green), Epilepsy (n = 16, blue) and Resistant (n = 8, red) groups. The Epilepsy group shows a tendency towards lower power throughout the power spectrum, though the differences in overall spectra between epilepsy status groups were not statistically significant (Kruskal-Wallis H test; p > 0.05). b Head plots demonstrate the spatial distribution of overall spectral power in No Epilepsy (left), Epilepsy (middle) and Resistant (right) groups. Dots represent electrode locations. Colour maps show relative power of the overall spectrum interpolated between electrodes. Colour maps were calculated using the maximum (red) and minimum (blue) across the entire population and applied to all groups, allowing direct comparison of power distribution between groups. The differences in power at each individual electrode were not statistically significant (Kruskal-Wallis H test p > 0.05). c Profile of hemispheric asymmetry at each frequency band by electrode location for No Epilepsy (left), Epilepsy (middle) and Resistant (right) groups. Each column represents a scalp location. Each row represents a frequency band. Cell colour is determined by the asymmetry of the corresponding band at the corresponding location, calculated by subtracting the power in that band at that location on one side from the other. Red indicates greater power in the left hemisphere, blue indicates greater power in the right hemisphere, and intensity indicates the magnitude of the asymmetry. The No Epilepsy group demonstrates a trend toward right hemispheric predominance in the overall spectrum, the Epilepsy group do not appear to demonstrate any hemispheric predominance, while the Resistant group show a tendency towards left hemispheric predominance in the overall spectrum; differences in the overall spectrum were statistically significant between groups (p < 0.05, Kruskal-Wallis H test)