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Table 3 Location and severity of observed MR Imaging abnormalities in newborns with good versus poor outcome

From: Prognostic value of early, conventional proton magnetic resonance spectroscopy in cooled asphyxiated infants

 

MRI abnormality and good outcome

(n = 13)

MRI abnormality and poor outcome

(n = 11)

p value

Location of injury

 Basal ganglia and thalami

6 (46%)

8 (72%)

0.2397

 Internal capsule

5 (38%)

6 (54%)

0.6824

 White matter

5 (38%)

0 (0%)

0.0411

 Cortex

1 (8%)

1 (9%)

> 0.9999

Severity of injury (MRI score)

 HIE score 1

3 (23%)

2 (18%)

> 0.9999

 HIE score 2

6 (46%)

3 (27%)

0.4225

 HIE score 3

0 (0%)

8 (72%)

0.0002*

  1. Abnormalities are described as signal intensity abnormality on T1/T2 weighted images, or diffusion abnormality. Severity of injury is described as MR imaging score of HIE [35], assigned by our neuroradiologist blinded to the newborns’ clinical condition
  2. * represents significant results surviving Bonferroni-correction (p < 0.0014)