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Table 2 Allele frequencies of the CTD and control groups

From: Genetic variation in folate metabolism is associated with the risk of conotruncal heart defects in a Chinese population

Genotyped SNPs Controls (n = 234) CTD (N = 193) p-Value for HWE test
% (No.) % (No.)
MTHFR C677T (rs1801133)
 C 61.1(286) 51.3(198) 0.004*
 T 38.9(182) 48.7(188)
MTHFR A1298C (rs1801131)
 A 61.3(287) 47.9(185) < 0.001*
 C 38.7(181) 52.1(201)
SLC19A1 G80A (rs1051266)
 G 59.8(280) 53.1(205) 0.0485*
 A 40.2(188) 46.9(181)
MTR A2576G (rs1805087)
 A 41.5(194) 61.9(239) 0.7862
 G 58.5(174) 38.1(147)
MTRR A66G (rs1801394)
 A 56.8(266) 60.6(234) 0.2639
 G 43.2(202) 39.4(152)
  1. HWE Hardy-Weinberg equilibrium
  2. *means p-value< 0.05