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Table 5 Pairwise comparison of receiving operating characteristic curves in preterm neonatal sepsis subgroups at the time of clinical suspicion of sepsis

From: The cut-off levels of procalcitonin and C-reactive protein and the kinetics of mean platelet volume in preterm neonates with sepsis

  95% CI P
EONS CRP 1 -EONS PCT 1
AUC CRP 1 = 0.838 AUC PCT 1 = 0.832
−0.061-0.074 0.851
LONS CRP 1- LONS PCT 1
AUC CRP 1 = 0.856 AUC PCT 1 = 0.820
−0.027-0.099 0.260
LONS MPV1- LONS CRP 1
AUC MPV 1 = 0.689 AUC CRP 1 = 0.856
0.091–0.243 < 0.001
LONS MPV1- LONS PCT 1
AUC MPV 1 = 0.689 AUC PCT 1 = 0.820
0.055–0.207 0.001
Clinical sepsis CRP 1- Clinical sepsis PCT 1
AUC CRP 1 = 0.779 AUC PCT 1 = 0.724
−0.021-0.131 0.155
Clinical sepsis CRP 1- Clinical sepsis MPV 1
AUC CRP 1 = 0.779 AUC MPV 1 = 0.606
0.086–0.259 < 0.001
Clinical sepsis PCT 1- Clinical sepsis MPV 1
AUC PCT 1 = 0.724 AUC MPV 1 = 0.606
0.033–0.202 0.006
Proven sepsis CRP 1-Proven sepsis PCT 1
AUC CRP 1 = 0.922 AUC PCT 1 = 0.939
−0.034–0.063 0.556
Proven sepsis CRP 1-Proven sepsis MPV 1
AUC CRP 1 = 0.922 AUC MPV 1 = 0.653
0.196–0.343 < 0.001
Proven sepsis MPV 1-Proven sepsis PCT 1
AUC MPV 1 = 0.606 AUC PCT 1 = 0.939
0.212–0.355 < 0.001
  1. EONS Early onset neonatal sepsis, LONS Late onset neonatal sepsis, AUC Area under curve: CRP C-reactive protein, PCT Procalcitonin, MPV Mean platelet volume