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Table 5 Pairwise comparison of receiving operating characteristic curves in preterm neonatal sepsis subgroups at the time of clinical suspicion of sepsis

From: The cut-off levels of procalcitonin and C-reactive protein and the kinetics of mean platelet volume in preterm neonates with sepsis

 

95% CI

P

EONS CRP 1 -EONS PCT 1

AUC CRP 1 = 0.838 AUC PCT 1 = 0.832

−0.061-0.074

0.851

LONS CRP 1- LONS PCT 1

AUC CRP 1 = 0.856 AUC PCT 1 = 0.820

−0.027-0.099

0.260

LONS MPV1- LONS CRP 1

AUC MPV 1 = 0.689 AUC CRP 1 = 0.856

0.091–0.243

< 0.001

LONS MPV1- LONS PCT 1

AUC MPV 1 = 0.689 AUC PCT 1 = 0.820

0.055–0.207

0.001

Clinical sepsis CRP 1- Clinical sepsis PCT 1

AUC CRP 1 = 0.779 AUC PCT 1 = 0.724

−0.021-0.131

0.155

Clinical sepsis CRP 1- Clinical sepsis MPV 1

AUC CRP 1 = 0.779 AUC MPV 1 = 0.606

0.086–0.259

< 0.001

Clinical sepsis PCT 1- Clinical sepsis MPV 1

AUC PCT 1 = 0.724 AUC MPV 1 = 0.606

0.033–0.202

0.006

Proven sepsis CRP 1-Proven sepsis PCT 1

AUC CRP 1 = 0.922 AUC PCT 1 = 0.939

−0.034–0.063

0.556

Proven sepsis CRP 1-Proven sepsis MPV 1

AUC CRP 1 = 0.922 AUC MPV 1 = 0.653

0.196–0.343

< 0.001

Proven sepsis MPV 1-Proven sepsis PCT 1

AUC MPV 1 = 0.606 AUC PCT 1 = 0.939

0.212–0.355

< 0.001

  1. EONS Early onset neonatal sepsis, LONS Late onset neonatal sepsis, AUC Area under curve: CRP C-reactive protein, PCT Procalcitonin, MPV Mean platelet volume