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Table 6 Univariable and multivariable analyses of clinical variables influencing relapse in CD

From: Study of disease phenotype and its association with prognosis of paediatric inflammatory bowel disease in China

Variables

Univariable analysis

Multivariable analysis (significant in univariate)

HR

95% CI

P value

HR

95% CI

P value

Age

 3–9 y vs 0–2 y

0.25

0.14–0.48

< 0.01

0.26

0.13–0.53

< 0.01

 10–16 y vs 0–2 y

0.20

0.11–0.36

< 0.01

0.23

0.12–0.44

< 0.01

Sex

 female vs male

0.84

0.52–1.36

0.47

   

Disease location

 L2 vs L1

2.18

0.98–4.84

0.06

   

 L3 vs L1

1.29

0.61–2.77

0.51

   

 L4 vs no L4

0.89

0.54–1.46

0.64

   

 Perianal disease, yes vs no

1.59

1.00–2.53

0.048

1.13

0.68–1.88

0.63

 Behaviour B2 vs not

1.04

0.66–1.64

0.87

   

 Behaviour B3 vs not

2.08

1.15–3.77

0.02

1.96

1.01–3.81

0.046

 Weight < -2SD vs not

1.71

1.04–2.82

0.04

0.96

0.54–1.69

0.88

 Growth impairment vs not

1.31

0. 83–2.09

0.25

   

 Top-down treatment vs not

0.69

0.40–1.21

0.20

   

 Steroid dependency vs not

2.26

1.40–3.64

< 0.01

1.88

1.16–3.06

0.01