From: Drug utilization in neonatal setting of Pakistan: focus on unlicensed and off label drug prescribing
S.No. | Variables | p- value | OR (95% CI) | ||
---|---|---|---|---|---|
Unlicensed prescriptions | |||||
Present (n = 1001) | Absence (n = 299) | ||||
1 | Gender | ||||
Female | 302 | 114 | 0.039** | 0.743 (0.560–0.985) | |
Male | 699 | 185 | Reference | ||
2 | Gestational age | ||||
Preterm infants | 174 | 97 | 0.000*** | 0.537 (0.396–.729) | |
Term infants | 827 | 202 | Reference | ||
3 | Length of Stay | ||||
5 or More days | 148 | 20 | 0.036** | 1.730 (1.037–2.888) | |
Less than 5 days | 855 | 279 | Reference | ||
4 | Prescribed drugs | ||||
3 or More drugs | 521 | 64 | 0.000*** | 3.360 (2.548–4.592) | |
Less than 2 drugs | 480 | 235 | Reference | ||
Off label prescriptions | |||||
Present (n = 1016) | Absence (n = 284) | ||||
1 | Gender | ||||
Female | 304 | 112 | 0.026** | 0.720 (0.539–0.962) | |
Male | 712 | 172 | Reference | ||
2 | Gestational age | ||||
Preterm infants | 179 | 76 | 0.854 | 0.970 (0.700–1.343) | |
Term infants | 837 | 208 | Reference | ||
3 | Length of Stay | ||||
5 or More days | 148 | 20 | 0.083* | 0.662 (0.415–1.055) | |
Less than 5 days | 855 | 279 | Reference | ||
4 | Prescribed drugs | ||||
3 or More drugs | 544 | 41 | 0.000*** | 7.187 (4.961–10.411) | |
Less than 2 drugs | 472 | 243 | Reference |