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Table 2 Correlations between BAP and CTX and characteristics of girls with CPP

From: Comparison of two bone markers with growth evolution in 74 girls with central precocious puberty

 

BAP

CTX

n

r

IC 95%

p

n

r

IC 95%

p

All patients

Age at onset of puberty (years)

62

−0.15

−0.40; 0.11

0.232

69

0.05

−0.2; 0.29

0.711

Age at initial evaluation (years)

62

−0.17

− 0.41; 0.09

0.180

69

0.01

−0.23; 0.25

0.941

BMI (SDS)

62

0.04

−0.22; 0.29

0.752

69

−0.04

−0.28; 0.21

0.761

Growth rate the year before initial evaluation (cm)

60

0.21

−0.05; 0.45

0.100

65

0.26

0.01; 0.48

0.035

Growth rate the year before initial evaluation (SDS)

60

0.10

−0.17; 0.35

0.446

65

0.34

0.09; 0.54

0.006

Height at initial evaluation (cm)

62

0,10

−0.16; 0.35

0.424

69

0.09

−0.16; .32

0.480

Height at initial evaluation (SDS)

62

0.31

0.06; 0.52

0.015

69

0.21

−0.03; 0.43

0.078

Bone age (years)

61

0.19

−0.08; 0.42

0.151

68

0.07

−0.18; 0.31

0.566

Difference between bone and chronological ages (years)

61

0.39

0.15; 0.59

0.002

68

0.07

−0.18; 0.31

0.566

BAP (μg/L)

 

57

0.19

−0.08; 0.44

0.153

Basal LH concentration (IU/L)

58

0.07

−0.20; 0.33

0.606

60

0.15

−0.11; 0.4

0.243

Basal FSH concentration (IU/L)

57

0.27

0.00; 0.50

0.042

59

−0.02

−0.28; 0.24

0.860

LH peak (IU/L)

62

0.24

−0.02; 0.47

0.063

69

0.12

−0.13; 0.35

0.346

FSH peak (IU/L)

62

0.10

−0.16; 0.35

0.448

69

0.01

−0.23; 0.25

0.935

LH/FSH peak ratio

62

0.14

−0.12; 0.39

0.263

69

0.10

−0.15; 0.33

0.415

Estradiol (pg/mL)

62

0.16

−0.10; 0.40

0.206

69

−0.06

−0.3; 0.19

0.618

Untreated patients

Growth rate 6 months following initial evaluation (SDS)

25

0.17

−0.25; 0.54

0.406

24

−0.02

−0.43; 0.40

0.928

Growth rate the year following initial evaluation (SDS)

13

0.31

−0.31; 0.74

0.306

13

−0.18

−0.67; 0.43

0.566

Adult height (cm)

19

0.58

0.16; 0.82

0.009

17

0.04

−0.46; 0.52

0.874

Adult height (SDS)

19

0.58

0.15; 0.82

0.009

17

0.04

−0.46; 0.53

0.869

Difference between target and adult heights (cm)

17

−0.19

−0.63; 0.33

0.453

15

−0.23

− 0.67; 0.33

0.404

  1. Serum BAP concentrations were available for 62 patients including 42 untreated patients
  2. Serum CTX concentrations were available for 69 patients including 44 untreated patients
  3. BAP bone alkaline phosphatase, CTX C-terminal telopeptide of type I collagen crosslinks, BMI body mass index, SDS standard deviation score, LH luteinizing hormone, FSH follicle stimulating hormone
  4. Bold data correspond to significant p values
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BMC Pediatrics

ISSN: 1471-2431

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