TY - JOUR AU - Kuo, Ho-Chang AU - Guo, Mindy Ming-Huey AU - Lo, Mao-Hung AU - Hsieh, Kai-Sheng AU - Huang, Ying-Hsien PY - 2018 DA - 2018/06/22 TI - Effectiveness of intravenous immunoglobulin alone and intravenous immunoglobulin combined with high-dose aspirin in the acute stage of Kawasaki disease: study protocol for a randomized controlled trial JO - BMC Pediatrics SP - 200 VL - 18 IS - 1 AB - Kawasaki disease (KD) is an acute febrile systemic vasculitis most commonly seen in children under 5 years old. High-dose aspirin is often administered, but the duration of such treatment varies. Many centers reduce the aspirin dose once the patient is afebrile, even before treating said patient with intravenous immunoglobulin (IVIG). However, a randomized controlled trial regarding high-dose aspirin in the acute stage of KD has not previously been carried out. SN - 1471-2431 UR - https://doi.org/10.1186/s12887-018-1180-1 DO - 10.1186/s12887-018-1180-1 ID - Kuo2018 ER -